Predictors of survival in patients with influenza pneumonia-related severe acute respiratory distress syndrome treated with prone positioning

Annals of Intensive Care

Table 2 Change in gas exchange and lung mechanics between survivors and non-survivors for influenza pneumonia-related ARDS

Parameters	30-day		p value	60-day		p value
Parameters	Survivors (n = 48)	Non-survivors (n = 17)	p value	Survivors (n = 45)	Non-survivors (n = 20)	p value
Δ PaO₂ (mm Hg)	6.0 ± 53.7	6.6 ± 29.1	0.963	5.2 ± 54.2	8.4 ± 29.0	0.823
Δ PaCO₂ (mm Hg)	− 4.7 ± 20.4	− 3.4 ± 14.3	0.817	− 5.2 ± 20.4	8.4 ± 29.0	0.823
Δ FiO₂	− 15.9 ± 19.6	− 12.9 ± 20.5	0.597	− 17.0 ± 19.8	− 11.0 ± 19.4	0.263
Δ PaO₂/FiO₂ (mm Hg)	34.7 ± 83.6	30.3 ± 49.7	0.839	35.5 ± 85.9	29.2 ± 47.4	0.706
Δ P(A–a)O₂ (mm Hg)	− 140.6 ± 173.7	− 94.3 ± 157.5	0.337	− 145.2 ± 175.4	− 90.8 ± 153.2	0.236
Δ Tidal volume (ml/kg PBW)	− 0.2 ± 1.6	− 0.5 ± 2.3	0.532	− 0.1 ± 1.6	− 0.6 ± 2.1	0.389
Δ PEEP (cm H₂O)	1.0 ± 3.1	1.4 ± 3.5	0.672	1.1 ± 3.2	1.2 ± 3.3	0.913
Δ Peak airway pressure (cm H₂O)	− 0.5 ± 3.3	1.5 ± 4.1	0.041*	− 0.6 ± 3.2	1.5 ± 3.8	0.024*
Δ Dynamic driving pressure (cm H₂O)	− 1.4 ± 3.3	0.1 ± 2.4	0.106	− 1.5 ± 3.3	0.3 ± 2.4	0.031*
Δ Dynamic compliance (ml/cm H₂O)	1.4 ± 7.9	− 2.6 ± 9.0	0.103	2.0 ± 7.7	− 3.2 ± 8.6	0.022*

ARDS acute respiratory distress syndrome, Δ change between before and after prone positioning 1 day, PaO₂ partial pressure of oxygen in arterial blood, PaCO₂ atrial pressure of carbon dioxide in arterial blood, FiO₂ oxygen fraction in air, P(A-a)O₂ alveolar–arterial oxygen gradient, PEEP positive end-expiratory pressure
All values are expressed as mean ± SD
*p < 0.05: survivors versus non-survivors