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Table 3 Cox regression analysis of clinical variables associated with 60-day mortality in influenza pneumonia-related ARDS with prone positioning

From: Predictors of survival in patients with influenza pneumonia-related severe acute respiratory distress syndrome treated with prone positioning

Clinical variables Univariate Multivariate
Hazard ratio (95% CI) p value Hazard ratio (95% CI) p value
APACHE II score 1.089 (1.035–1.147) 0.001* 1.042 (0.982–1.106) 0.178
PSI 1.015 (1.005–1.026) 0.003* 1.020 (1.009–1.032) < 0.001*
Renal replacement therapy 5.355 (2.159–13.281) 0.000* 6.248 (2.245–17.389) < 0.001*
Δ Peak airway pressure (cm H2O) 1.143 (1.019–1.282) 0.022* 0.996 (0.822–1.208) 0.969
Δ Dynamic driving pressure (cm H2O) 1.147 (1.008–1.305) 0.037* 1.372 (1.095–1.718) 0.006*
Δ Dynamic compliance (ml/cm H2O) 0.925 (0.871–0.983) 0.011* 0.941 (0.872–1.015) 0.117
  1. ARDS acute respiratory distress syndrome, CI confidence interval, APACHE II Acute Physical and Chronic Health Evaluation, PSI pneumonia severity index, Δ difference between before and after prone positioning 1 day
  2. *p < 0.05