Fig. 2

Scenarios for both estimated cumulative MES and MEC. Values are depicted as mean ± 95% CI. The 95% CI is represented by the dotted lines. The first values reflect levels at ICU admission, when storage was assumed to be zero. In all scenarios, there were considerable MES and MEC after 4 days of ICU admission. a With stable sodium levels, MES is mostly influenced by altering the insensible perspiration. b MEC showed a similar pattern as MES, but was slightly more affected by the changes in the extracellular compartment than MES