Estimation of sodium and chloride storage in critically ill patients: a balance study

Annals of Intensive Care

Table 2 Cumulative data on fluid and electrolyte administration

	Day 1	Day 2	Day 3	Day 4	P*
Intake
Fluid (L)	3.6 ± 0.4	7.9 ± 0.5	11.0 ± 0.5	13.6 ± 0.6
Sodium (mmol)	460 ± 52	935 ± 67	1235 ± 72	1441 ± 75
Chloride^a (mmol)	420 ± 53	872 ± 68	1162 ± 79	1377 ± 76
Output
Fluid (L)	1.6 ± 0.1	3.9 ± 0.2	6.5 ± 0.3	8.9 ± 0.3
Sodium (mmol)	139 ± 14	293 ± 23	472 ± 30	626 ± 35
Chloride^a (mmol)	117 ± 17	255 ± 28	418 ± 43	574 ± 47
Balance
Fluid (L)	1.9 ± 0.3	3.7 ± 0.5	4.0 ± 0.5	3.9 ± 0.6
Sodium (mmol)	321 ± 47	642 ± 62	769 ± 72	822 ± 76
Chloride^a (mmol)	274 ± 51	498 ± 66	535 ± 82	556 ± 82
Plasma sodium (mmol/L)	137.1 ± 0.5	136.6 ± 0.5	136.2 ± 0.6	136.9 ± 0.5	0.741
Plasma chloride^a (mmol/L)	109.8 ± 0.9	109.3 ± 0.8	108.2 ± 0.9	108.0 ± 0.9	0.107

Data are depicted as mean ± SE
* Difference between day 1 and day 4
^aChloride data were available for 27, 27, 24 and 28 patients, respectively, on day 1 to day 4