When timing and dose of nutrition support were examined, the modified Nutrition Risk in Critically Ill (mNUTRIC) score did not differentiate high-risk patients who would derive the most benefit from nutrition support: a prospective cohort study

Annals of Intensive Care

Table 3 Association between energy (and protein) intake and 28-day mortality in low- and high-risk patients stratified by days on exclusive nutrition support

Energy/protein intake	Short-term exclusive nutrition support (≤ 6 days)			Longer-term exclusive nutrition support (≥ 7 days)
Energy/protein intake	Low risk^a (n = 42)	High risk^a (n = 64)	Interaction	Low risk^a (n = 73)	High risk^a (n = 73)	Interaction
Energy intake (each 10% of goal)	0.93 (0.67, 1.28) p = 0.657	1.37 (1.17, 1.61) p < 0.001	p = 0.280	1.18 (0.75, 1.84) p =0.474	0.87 (0.73, 1.04) p =0.135	p = 0.127
Protein intake (each 10% of goal)	0.97 (0.70, 1.33) p =0.846	1.31 (1.10, 1.56) p =0.002	p = 0.405	1.02 (0.69, 1.51) p =0.913	0.78 (0.66, 0.93) p =0.006	p = 0.088

Values are hazard ratio (95% CI) adjusted for exposure to cardiopulmonary resuscitation before admission to the intensive care unit, nutritional status, and days on exclusive nutrition support
^a Low and high risk is defined as scores “0–5” and “6–9” of the modified Nutrition Risk in Critically Ill (mNUTRIC) score, respectively [9]