Variables | Moderate-to-large pleural effusion | p value | |
---|---|---|---|
Absent (n = 168) | Present (n = 81) | ||
Male gender | 98 (58%) | 52 (64%) | 0.38 |
Age (years) | 61 [50–72] | 69 [60–80] | < 0.001 |
SAPS II score at ICU admission | 49 [37–62] | 52 [41–67] | 0.07 |
Comorbidities | |||
Neurological disease | 22 (13%) | 6 (7%) | 0.18 |
Cardiac disease | 93 (55%) | 65 (80%) | < 0.001 |
Cirrhosis | 12 (7%) | 9 (11%) | 0.29 |
Chronic renal failure | 22 (13%) | 16 (20%) | 0.17 |
Cancer or hematological malignancy | 16 (10%) | 22 (27%) | < 0.001 |
Main reason for intubation | |||
Coma | 54 (32%) | 9 (11%) | < 0.001 |
Acute respiratory failure | 51 (30%) | 37 (46%) | 0.02 |
Septic shock | 22 (13%) | 12 (15%) | 0.71 |
Others | 41 (24%) | 23 (28%) | 0.5 |
From ICU admission to first SBT | |||
ARDS | 32 (19%) | 23 (28%) | 0.096 |
Duration of MV before the first SBT | 4 [2–7] | 4 [3–9] | 0.09 |
Dialysis | 15 (9%) | 16 (20%) | 0.015 |
Biological and ultrasound data at first SBT | |||
Serum creatinine (µmol/L) | 74 [55–119] | 90 [60–164] | 0.07 |
Serum protide (mg/L) | 59 [54–66] | 59 [51–63] | 0.19 |
Bilateral pleural effusion | 16 (10%) | 60 (74%) | < 0.001 |
Maximal interpleural distance (mm) | 0 [0–5] | 27 [20–41] | < 0.001 |
Condensation or atelectasis of lung adjacent to the pleural effusion at ultrasound | – | 68 (84%) | |
Left ventricle ejection fraction (%) | 60 [50–60] | 50 [39–60] | < 0.001 |
Outcome | |||
Pleural effusion drainage during weaning | 0 | 4 (5%) | 0.005 |
Prophylactic NIV post-extubation | 62 (38%) | 33 (43%) | 0.39 |
Failure of the first SBT | 19 (11%) | 27 (33%) | < 0.001 |
Extubation failure | 24 (15%) | 15 (20%) | 0.31 |
Weaning failurea | 36 (22%) | 37 (47%) | < 0.001 |
Weaning groupb | 0.03 | ||
Short weaning | 118 (70%) | 43 (53%) | |
Difficult weaning | 38 (20%) | 26 (32%) | |
Prolonged weaning | 16 (10%) | 12 (15%) | |
Tracheotomy | 4 (2%) | 2 (3%) | 0.97 |
VFD from first SBT to day 28 (days) | 23 [16–26] | 21 [5–24] | 0.01 |
Death in ICU | 14 (8%) | 13 (16%) | 0.07 |
Death at day 28 | 14 (8%) | 14 (17%) | 0.04 |