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Table 1 Demographic and clinical characteristics of intensive care unit patients with distributive shock in the MIMIC-III database, 2001–2012

From: Mean arterial pressure and mortality in patients with distributive shock: a retrospective analysis of the MIMIC-III database

Characteristic High-dose subgroupa Non-high dose All patients
(N = 2066) (N = 3281) (N = 5347)
Sex N (%)    
 Female 943 (45.6) 1548 (47.2) 2491 (46.6)
 Male 1123 (54.4) 1733 (52.8) 2856 (53.4)
Age, years    
 Mean (SD) 65.4 (15.8) 66.8 (15.6) 66.3 (15.7)
Body weight (kgs)b    
 Mean (SD) 81.3 (25.3) 81.8 (25.2) 81.6 (25.2)
 Missing, N (%) 26 (1.3) 31 (0.9) 57 (1.1)
Mean arterial pressure (MAP)b    
 Mean (SD) 72.5 (18.9) 75.9 (20.1) 74.6 (19.7)
 Missing, N (%) 120 (5.8) 209 (6.4) 329 (6.2)
 Number (%) of patients with    
  < 65 mmHg 694 (35.7) 852 (27.7) 1546 (30.8)
  < 60 mmHg 459 (23.6) 515 (16.8) 974 (19.4)
  < 55 mmHg 269 (13.8) 296 (9.6) 565 (11.3)
Lactate concentration (mmol/L)b    
 Mean (SD) 3.7 (3.0) 2.5 (2.1) 3.0 (2.6)
 Missing, N (%) 501 (24.2) 866 (26.4) 1367 (25.6)
Albumin concentration (g/L)b    
 Mean (SD) 2.7 (0.7) 2.9 (0.7) 2.9 (0.7)
 Missing, N (%) 1103 (53.4) 2019 (61.5) 3122 (58.4)
Creatinine (mg/dL)b    
 Mean (SD) 2.1(1.9) 1.9 (1.8) 2.0 (1.9)
 Missing, N (%) 114 (5.5) 180 (5.5) 294 (5.5)
Baseline mechanical ventilation statusb    
 No, N (%) 880 (42.6) 1725 (52.6) 2605 (48.7)
 Yes, N (%) 1186 (57.4) 1556 (47.4) 2742 (51.3)
Baseline continuous renal replacement therapyb    
 No, N (%) 2046 (99.0) 3261 (99.4) 5307 (99.3)
 Yes, N (%) 20 (1.0) 20 (0.6) 40 (0.7)
SOFA scoreb    
 Mean (SD) 9.0 (4.0) 6.4 (3.2) 7.4 (3.8)
Hypertension    
 No, N (%) 1457 (70.5) 2159 (65.8) 3616 (67.6)
 Yes, N (%) 609 (29.5) 1122 (34.2) 1731 (32.4)
Severe sepsis or septic shock    
 No, N (%) 1195 (36.4) 389 (18.8) 1584 (29.6)
 Yes, N (%) 2086 (63.6) 1677 (81.2) 3763 (70.4)
Maximum NED during treatment    
 Mean (SD) 1.18 (3.45) 0.32 (2.44) 0.65 (2.90)
  1. NED norepinephrine-equivalent dose
  2. aHigh-dose vasopressor subgroup is defined as NED ≥ 0.2 µg/kg/min for ≥ 6 h between ICU admission and discharge
  3. bAt initiation of vasopressor therapy