Table 1 Demographic and clinical characteristics of intensive care unit patients with distributive shock in the MIMIC-III database, 2001–2012
Characteristic | High-dose subgroupa | Non-high dose | All patients |
|---|---|---|---|
(N = 2066) | (N = 3281) | (N = 5347) | |
Sex N (%) | |||
Female | 943 (45.6) | 1548 (47.2) | 2491 (46.6) |
Male | 1123 (54.4) | 1733 (52.8) | 2856 (53.4) |
Age, years | |||
Mean (SD) | 65.4 (15.8) | 66.8 (15.6) | 66.3 (15.7) |
Body weight (kgs)b | |||
Mean (SD) | 81.3 (25.3) | 81.8 (25.2) | 81.6 (25.2) |
Missing, N (%) | 26 (1.3) | 31 (0.9) | 57 (1.1) |
Mean arterial pressure (MAP)b | |||
Mean (SD) | 72.5 (18.9) | 75.9 (20.1) | 74.6 (19.7) |
Missing, N (%) | 120 (5.8) | 209 (6.4) | 329 (6.2) |
Number (%) of patients with | |||
< 65 mmHg | 694 (35.7) | 852 (27.7) | 1546 (30.8) |
< 60 mmHg | 459 (23.6) | 515 (16.8) | 974 (19.4) |
< 55 mmHg | 269 (13.8) | 296 (9.6) | 565 (11.3) |
Lactate concentration (mmol/L)b | |||
Mean (SD) | 3.7 (3.0) | 2.5 (2.1) | 3.0 (2.6) |
Missing, N (%) | 501 (24.2) | 866 (26.4) | 1367 (25.6) |
Albumin concentration (g/L)b | |||
Mean (SD) | 2.7 (0.7) | 2.9 (0.7) | 2.9 (0.7) |
Missing, N (%) | 1103 (53.4) | 2019 (61.5) | 3122 (58.4) |
Creatinine (mg/dL)b | |||
Mean (SD) | 2.1(1.9) | 1.9 (1.8) | 2.0 (1.9) |
Missing, N (%) | 114 (5.5) | 180 (5.5) | 294 (5.5) |
Baseline mechanical ventilation statusb | |||
No, N (%) | 880 (42.6) | 1725 (52.6) | 2605 (48.7) |
Yes, N (%) | 1186 (57.4) | 1556 (47.4) | 2742 (51.3) |
Baseline continuous renal replacement therapyb | |||
No, N (%) | 2046 (99.0) | 3261 (99.4) | 5307 (99.3) |
Yes, N (%) | 20 (1.0) | 20 (0.6) | 40 (0.7) |
SOFA scoreb | |||
Mean (SD) | 9.0 (4.0) | 6.4 (3.2) | 7.4 (3.8) |
Hypertension | |||
No, N (%) | 1457 (70.5) | 2159 (65.8) | 3616 (67.6) |
Yes, N (%) | 609 (29.5) | 1122 (34.2) | 1731 (32.4) |
Severe sepsis or septic shock | |||
No, N (%) | 1195 (36.4) | 389 (18.8) | 1584 (29.6) |
Yes, N (%) | 2086 (63.6) | 1677 (81.2) | 3763 (70.4) |
Maximum NED during treatment | |||
Mean (SD) | 1.18 (3.45) | 0.32 (2.44) | 0.65 (2.90) |