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Table 2 Percentage of patients with longest continuous episode of mean arterial pressure (MAP) below 80 mmHg, 75 mmHg, 65 mmHg, 60 mmHg, and 55 mmHg over total intensive care unit stay and dosing of vasopressors in patients with distributive shock in the MIMIC-III database, for the periods of 2001–2012, 2001–2008, and 2008–2012

From: Mean arterial pressure and mortality in patients with distributive shock: a retrospective analysis of the MIMIC-III database

Measure

Ever below

≥ 2 h

≥ 4 h

≥ 8 h

≥ 12 h

≥ 16 h

≥ 20 h

Continuous time below MAP threshold during vasopressor therapy 2001–2012

 All patients, % (N = 5347)

  MAP < 80 mmHg

99.3

95.7

87.3

67.0

49.8

37.3

28.6

  MAP < 75 mmHg

98.7

91.0

77.4

51.1

34.1

23.4

16.7

  MAP < 65 mmHg

93.4

62.0

35.0

14.1

7.3

4.1

2.7

  MAP < 60 mmHg

83.7

36.0

15.2

5.3

2.6

1.5

0.9

  MAP < 55 mmHg

67.6

17.2

6.0

2.4

1.2

0.6

0.4

Continuous time below MAP threshold during vasopressor therapy 2001–2008

 All patients, % (N = 3173)

  MAP < 80 mmHg

99.1

95.1

86.4

67.0

50.4

38.3

29.6

  MAP < 75 mmHg

98.1

89.9

76.3

51.3

34.8

24.3

17.6

  MAP < 65 mmHg

92.1

60.7

35.0

15.0

8.0

4.6

2.9

  MAP < 60 mmHg

81.1

35.7

15.6

6.0

3.1

1.7

0.9

  MAP < 55 mmHg

64.5

17.8

6.6

2.8

1.3

0.7

0.4

Continuous time below MAP threshold during vasopressor therapy 2008–2012

 All patients, % (N = 2174)

  MAP < 80 mmHg

99.8

96.7

88.6

67.1

48.9

35.9

27.0

  MAP < 75 mmHg

99.4

92.5

79.0

50.8

32.9

22.2

15.3

  MAP < 65 mmHg

95.3

63.8

35.1

12.7

6.3

3.4

2.3

  MAP < 60 mmHg

87.4

36.7

14.6

4.3

1.9

1.2

0.9

  MAP < 55 mmHg

72.1

16.4

5.3

1.9

1.1

0.5

0.4