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Table 2 Percentage of patients with longest continuous episode of mean arterial pressure (MAP) below 80 mmHg, 75 mmHg, 65 mmHg, 60 mmHg, and 55 mmHg over total intensive care unit stay and dosing of vasopressors in patients with distributive shock in the MIMIC-III database, for the periods of 2001–2012, 2001–2008, and 2008–2012

From: Mean arterial pressure and mortality in patients with distributive shock: a retrospective analysis of the MIMIC-III database

Measure Ever below ≥ 2 h ≥ 4 h ≥ 8 h ≥ 12 h ≥ 16 h ≥ 20 h
Continuous time below MAP threshold during vasopressor therapy 2001–2012
 All patients, % (N = 5347)
  MAP < 80 mmHg 99.3 95.7 87.3 67.0 49.8 37.3 28.6
  MAP < 75 mmHg 98.7 91.0 77.4 51.1 34.1 23.4 16.7
  MAP < 65 mmHg 93.4 62.0 35.0 14.1 7.3 4.1 2.7
  MAP < 60 mmHg 83.7 36.0 15.2 5.3 2.6 1.5 0.9
  MAP < 55 mmHg 67.6 17.2 6.0 2.4 1.2 0.6 0.4
Continuous time below MAP threshold during vasopressor therapy 2001–2008
 All patients, % (N = 3173)
  MAP < 80 mmHg 99.1 95.1 86.4 67.0 50.4 38.3 29.6
  MAP < 75 mmHg 98.1 89.9 76.3 51.3 34.8 24.3 17.6
  MAP < 65 mmHg 92.1 60.7 35.0 15.0 8.0 4.6 2.9
  MAP < 60 mmHg 81.1 35.7 15.6 6.0 3.1 1.7 0.9
  MAP < 55 mmHg 64.5 17.8 6.6 2.8 1.3 0.7 0.4
Continuous time below MAP threshold during vasopressor therapy 2008–2012
 All patients, % (N = 2174)
  MAP < 80 mmHg 99.8 96.7 88.6 67.1 48.9 35.9 27.0
  MAP < 75 mmHg 99.4 92.5 79.0 50.8 32.9 22.2 15.3
  MAP < 65 mmHg 95.3 63.8 35.1 12.7 6.3 3.4 2.3
  MAP < 60 mmHg 87.4 36.7 14.6 4.3 1.9 1.2 0.9
  MAP < 55 mmHg 72.1 16.4 5.3 1.9 1.1 0.5 0.4