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Table 3 Multivariable logistic regression analyzing intensive care unit mortality and the longest episode of hypotension time below threshold of 65 mmHg

From: Mean arterial pressure and mortality in patients with distributive shock: a retrospective analysis of the MIMIC-III database

Parameter Estimate Standard error Wald Chi-square Pr > ChiSq Odds ratio
Intercept − 3.39 0.23 219.19 < 0.0001 0.03
MAP at initiation of vasopressors (vs. ≥ 65 mmHg)      
 < 65 mmHg 0.15 0.07 4.29 0.0384 1.16
 Missing − 0.36 0.16 5.10 0.024 0.70
Longest episode with MAP < 65 mmHg (vs. never below), hours      
 > 0 to < 2 0.57 0.20 7.88 0.005 1.76
 ≥ 2 to < 4 0.66 0.20 10.38 0.0013 1.93
 ≥ 4 to < 6 0.80 0.21 14.19 0.0002 2.23
 ≥ 6 to < 8 1.06 0.23 22.15 < 0.0001 2.90
 ≥ 8 to < 10 1.24 0.25 25.04 < 0.0001 3.44
 ≥ 10 to < 12 1.47 0.27 29.19 < 0.0001 4.36
 ≥ 12 to < 16 1.67 0.26 40.46 < 0.0001 5.30
 ≥ 16 to < 20 1.70 0.32 27.87 < 0.0001 5.47
 ≥ 20 1.96 0.28 49.20 < 0.0001 7.10
Max catecholamine dose (vs. 0 to < 0.2), NED      
 ≥ 0.2 to < 0.5 0.64 0.09 50.58 < 0.0001 1.89
 ≥ 0.5 to < 1.0 1.44 0.10 195.55 < 0.0001 4.24
 ≥ 1.0 to < 1.5 1.85 0.14 174.34 < 0.0001 6.37
 ≥ 1.5 to < 2.0 2.07 0.24 73.03 < 0.0001 7.95
 ≥ 2.0 to < 2.5 2.08 0.31 45.37 < 0.0001 7.97
 ≥ 2.5 1.61 0.20 63.21 < 0.0001 4.99
Age (vs. < 65), years      
 65–74 0.33 0.09 12.48 0.0004 1.39
 75–84 0.48 0.09 28.23 < 0.0001 1.62
 ≥ 85 0.73 0.11 44.40 < 0.0001 2.07
Female (vs. male) − 0.07 0.07 0.92 0.3364 0.94
Severe sepsis/septic shock (vs. none) − 0.19 0.08 5.44 0.0197 0.83
SOFA score (vs. ≤ 4)      
 > 4 to ≤ 6 0.03 0.11 0.07 0.7851 1.03
 > 6 to ≤ 8 0.09 0.11 0.58 0.4447 1.09
 > 8 to ≤ 10 0.32 0.12 6.75 0.0094 1.37
 > 10 1.09 0.12 83.90 < 0.0001 2.98
Hypertension (vs. none) − 0.02 0.08 0.09 0.7674 0.98
Baseline mechanical ventilation (vs. none) 0.15 0.07 4.45 0.035 1.16
Baseline continuous renal replacement therapy (vs. none) 1.26 0.38 11.19 0.0008 3.54
Albumin level (vs. ≥ 2.5 g/dL)      
 < 2.5 g/dL 0.60 0.11 29.41 < 0.0001 1.83
 Missing 0.18 0.08 5.01 0.0252 1.20
Creatinine level (vs. < 2.0 mg/dL)      
 ≥ 2.0 mg/dL − 0.09 0.08 1.14 0.2863 0.92
 Missing − 0.55 0.17 10.07 0.0015 0.57
Lactate level (vs. < 2.0 mmol/L)      
 ≥ 2.0 mmol/L 0.38 0.08 20.66 < 0.0001 1.46
 Missing 0.37 0.10 14.90 0.0001 1.45