|
Intercept
|
− 3.39
|
0.23
|
219.19
|
< 0.0001
|
0.03
|
|
MAP at initiation of vasopressors (vs. ≥ 65 mmHg)
| | | | | |
|
< 65 mmHg
|
0.15
|
0.07
|
4.29
|
0.0384
|
1.16
|
|
Missing
|
− 0.36
|
0.16
|
5.10
|
0.024
|
0.70
|
|
Longest episode with MAP < 65 mmHg (vs. never below), hours
| | | | | |
|
> 0 to < 2
|
0.57
|
0.20
|
7.88
|
0.005
|
1.76
|
|
≥ 2 to < 4
|
0.66
|
0.20
|
10.38
|
0.0013
|
1.93
|
|
≥ 4 to < 6
|
0.80
|
0.21
|
14.19
|
0.0002
|
2.23
|
|
≥ 6 to < 8
|
1.06
|
0.23
|
22.15
|
< 0.0001
|
2.90
|
|
≥ 8 to < 10
|
1.24
|
0.25
|
25.04
|
< 0.0001
|
3.44
|
|
≥ 10 to < 12
|
1.47
|
0.27
|
29.19
|
< 0.0001
|
4.36
|
|
≥ 12 to < 16
|
1.67
|
0.26
|
40.46
|
< 0.0001
|
5.30
|
|
≥ 16 to < 20
|
1.70
|
0.32
|
27.87
|
< 0.0001
|
5.47
|
|
≥ 20
|
1.96
|
0.28
|
49.20
|
< 0.0001
|
7.10
|
|
Max catecholamine dose (vs. 0 to < 0.2), NED
| | | | | |
|
≥ 0.2 to < 0.5
|
0.64
|
0.09
|
50.58
|
< 0.0001
|
1.89
|
|
≥ 0.5 to < 1.0
|
1.44
|
0.10
|
195.55
|
< 0.0001
|
4.24
|
|
≥ 1.0 to < 1.5
|
1.85
|
0.14
|
174.34
|
< 0.0001
|
6.37
|
|
≥ 1.5 to < 2.0
|
2.07
|
0.24
|
73.03
|
< 0.0001
|
7.95
|
|
≥ 2.0 to < 2.5
|
2.08
|
0.31
|
45.37
|
< 0.0001
|
7.97
|
|
≥ 2.5
|
1.61
|
0.20
|
63.21
|
< 0.0001
|
4.99
|
|
Age (vs. < 65), years
| | | | | |
|
65–74
|
0.33
|
0.09
|
12.48
|
0.0004
|
1.39
|
|
75–84
|
0.48
|
0.09
|
28.23
|
< 0.0001
|
1.62
|
|
≥ 85
|
0.73
|
0.11
|
44.40
|
< 0.0001
|
2.07
|
|
Female (vs. male)
|
− 0.07
|
0.07
|
0.92
|
0.3364
|
0.94
|
|
Severe sepsis/septic shock (vs. none)
|
− 0.19
|
0.08
|
5.44
|
0.0197
|
0.83
|
|
SOFA score (vs. ≤ 4)
| | | | | |
|
> 4 to ≤ 6
|
0.03
|
0.11
|
0.07
|
0.7851
|
1.03
|
|
> 6 to ≤ 8
|
0.09
|
0.11
|
0.58
|
0.4447
|
1.09
|
|
> 8 to ≤ 10
|
0.32
|
0.12
|
6.75
|
0.0094
|
1.37
|
|
> 10
|
1.09
|
0.12
|
83.90
|
< 0.0001
|
2.98
|
|
Hypertension (vs. none)
|
− 0.02
|
0.08
|
0.09
|
0.7674
|
0.98
|
|
Baseline mechanical ventilation (vs. none)
|
0.15
|
0.07
|
4.45
|
0.035
|
1.16
|
|
Baseline continuous renal replacement therapy (vs. none)
|
1.26
|
0.38
|
11.19
|
0.0008
|
3.54
|
|
Albumin level (vs. ≥ 2.5 g/dL)
| | | | | |
|
< 2.5 g/dL
|
0.60
|
0.11
|
29.41
|
< 0.0001
|
1.83
|
|
Missing
|
0.18
|
0.08
|
5.01
|
0.0252
|
1.20
|
|
Creatinine level (vs. < 2.0 mg/dL)
| | | | | |
|
≥ 2.0 mg/dL
|
− 0.09
|
0.08
|
1.14
|
0.2863
|
0.92
|
|
Missing
|
− 0.55
|
0.17
|
10.07
|
0.0015
|
0.57
|
|
Lactate level (vs. < 2.0 mmol/L)
| | | | | |
|
≥ 2.0 mmol/L
|
0.38
|
0.08
|
20.66
|
< 0.0001
|
1.46
|
|
Missing
|
0.37
|
0.10
|
14.90
|
0.0001
|
1.45
|
