Skip to main content

Table 2 Parameters at the peak level of C-reactive protein stratified for survival and non-survival

From: Inflammatory and coagulatory parameters linked to survival in critically ill children with sepsis

Parametersa Total (n = 250) Survivors (n = 209) Non-survivors (n = 41) Estimate with 95% CIb p valuec Not knownd
C-reactive protein (mg/dl) 18.5 (9.8–28.4) 18.6 (10–28) 17.6 (7.9–31.9) − 0.13 (− 5.3 to 4.55) 0.9491 0/0
Fibrinogen (mg/dl) 506 (329–675) 518 (383–685) 279 (173–514) 206 (118 to 289) < 0.0001 56/9
Platelets (G/l) 124 (50–232) 147 (62.5–247) 63 (29–98) 74 (37 to 111) < 0.0001 5/0
aPTT (s) 47 (38–56) 46 (36–53) 64 (53.5–83) − 20 (− 28 to − 13) < 0.0001 59/15
PT (%) 71 (51–84) 74 (55–85) 49 (36–71.5) 20 (10 to 30) 0.0001 59/14
Antithrombin (%) 63 (47–81) 65.5 (50–82) 51 (40–66) 14 (5 to 23) 0.0045 75/10
Leukocytes (G/l) 10.4 (4.6–17.8) 11.1 (5.3–17.5) 8.2 (3–20) 1.4 (− 1.6 to 5.1) 0.3342 4/5
  1. aData are presented as medians (25th–75th percentile)
  2. bEstimated median difference
  3. cDifferences between survivors and non-survivors assessed with Wilcoxon rank sum test for continuous variables
  4. dNumber of missing measurements in survivors/non-survivors