From: Validation of a new WIND classification compared to ICC classification for weaning outcome
Variables | ICC classification | WIND classification | ||||||
---|---|---|---|---|---|---|---|---|
Simple (n = 503) | Difficult (n = 145) | Prolonged (n = 87) | P for trend | Group 1 (n = 617) | Group 2 (n = 186) | Group 3 (n = 217) | P for trend | |
Age, years | 65 (53–72) | 68 (55–75) | 67 (55–75) | 0.081 | 65 (54–73) | 66 (56–74) | 66 (54–73) | 0.774 |
Sex, male | 351 (69.8) | 93 (64.1) | 64 (73.6) | 0.952 | 427 (69.2) | 127 (68.3) | 147 (67.7) | 0.673 |
Underlying disease | ||||||||
Malignancy | 249 (49.5) | 81 (55.9) | 61 (70.1) | < 0.001 | 296 (48.0) | 116 (62.4) | 151 (69.6) | < 0.001 |
Respiratory | 135 (26.8) | 42 (29.0) | 31 (35.6) | 0.106 | 163 (26.4) | 57 (30.6) | 82 (37.8) | 0.002 |
Neurologic | 62 (12.3) | 24 (16.6) | 17 (19.5) | 0.042 | 94 (15.2) | 35 (18.8) | 36 (16.6) | 0.484 |
Gastrointestinal | 54 (10.7) | 17 (11.7) | 3 (3.4) | 0.108 | 68 (11.0) | 20 (10.8) | 13 (6.0) | 0.048 |
Cardiovascular | 76 (15.1) | 17 (11.7) | 10 (11.5) | 0.239 | 92 (14.9) | 21 (11.3) | 24 (11.1) | 0.108 |
Genitourinary | 74 (14.7) | 17 (11.7) | 10 (11.5) | 0.292 | 90 (14.6) | 12 (6.5) | 21 (9.7) | 0.014 |
Interval between hospital admission and ICU admission, days | 1 (0–6) | 1 (0–7) | 3 (1–11) | 0.001 | 1 (0–7) | 2 (0–8) | 3 (1–14) | < 0.001 |
Cause of respiratory failure | ||||||||
Pneumonia | 170 (33.8) | 49 (33.8) | 46 (52.9) | 0.004 | 211 (34.2) | 62 (33.3) | 97 (44.7) | 0.013 |
Extrapulmonary sepsis | 104 (20.7) | 30 (20.7) | 10 (11.5) | 0.095 | 111 (18.0) | 38 (20.4) | 31 (14.3) | 0.343 |
ARDS | 40 (8.0) | 15 (10.3) | 9 (10.3) | 0.326 | 50 (8.1) | 14 (7.5) | 27 (12.4) | 0.087 |
CPR | 31 (6.2) | 8 (5.5) | 2 (2.3) | 0.204 | 39 (6.3) | 11 (5.9) | 9 (4.1) | 0.259 |
Coma | 23 (4.6) | 8 (5.5) | 6 (6.9) | 0.396 | 35 (5.7) | 10 (5.4) | 14 (6.5) | 0.725 |
Pulmonary edema | 45 (8.9) | 10 (6.9) | 1 (1.1) | 0.014 | 48 (7.8) | 9 (4.8) | 4 (1.8) | 0.001 |
Ventilatory failure | 28 (5.6) | 9 (6.2) | 2 (2.3) | 0.409 | 34 (5.5) | 11 (5.9) | 6 (2.8) | 0.159 |
Central airway obstruction | 14 (2.8) | 2 (1.4) | 3 (3.4) | 1.000 | 30 (4.9) | 9 (4.8) | 5 (2.3) | 0.143 |
Exacerbation of ILD | 12 (2.4) | 3 (2.1) | 2 (2.3) | 1.000 | 13 (2.1) | 4 (2.2) | 4 (1.8) | 0.894 |
Others | 36 (7.2) | 11 (7.6) | 6 (6.9) | 1.000 | 46 (7.5) | 18 (9.7) | 20 (9.2) | 0.332 |
SAPS III on ICU admission | 61 (50–73) | 63 (54–76) | 64 (53–77) | 0.046 | 61 (50–73) | 63 (54–76) | 65 (55–76) | 0.001 |
SOFA score on ICU admission | 8 (5–11) | 8 (5–11) | 8 (5–11) | 0.514 | 8 (5–11) | 8 (5–11) | 9 (5–12) | 0.063 |
Interval between hospital admission and intubation, days | 1 (0–8) | 2 (0–8) | 3 (1–14) | < 0.001 | 1 (0–8) | 3 (1–10) | 4 (1–16) | < 0.001 |