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Table 3 Comparison of baseline characteristics according to ICC and WIND classifications

From: Validation of a new WIND classification compared to ICC classification for weaning outcome

Variables ICC classification WIND classification
Simple
(n = 503)
Difficult
(n = 145)
Prolonged
(n = 87)
P for trend Group 1
(n = 617)
Group 2
(n = 186)
Group 3
(n = 217)
P for trend
Age, years 65 (53–72) 68 (55–75) 67 (55–75) 0.081 65 (54–73) 66 (56–74) 66 (54–73) 0.774
Sex, male 351 (69.8) 93 (64.1) 64 (73.6) 0.952 427 (69.2) 127 (68.3) 147 (67.7) 0.673
Underlying disease
 Malignancy 249 (49.5) 81 (55.9) 61 (70.1) < 0.001 296 (48.0) 116 (62.4) 151 (69.6) < 0.001
 Respiratory 135 (26.8) 42 (29.0) 31 (35.6) 0.106 163 (26.4) 57 (30.6) 82 (37.8) 0.002
 Neurologic 62 (12.3) 24 (16.6) 17 (19.5) 0.042 94 (15.2) 35 (18.8) 36 (16.6) 0.484
 Gastrointestinal 54 (10.7) 17 (11.7) 3 (3.4) 0.108 68 (11.0) 20 (10.8) 13 (6.0) 0.048
 Cardiovascular 76 (15.1) 17 (11.7) 10 (11.5) 0.239 92 (14.9) 21 (11.3) 24 (11.1) 0.108
 Genitourinary 74 (14.7) 17 (11.7) 10 (11.5) 0.292 90 (14.6) 12 (6.5) 21 (9.7) 0.014
Interval between hospital admission and ICU admission, days 1 (0–6) 1 (0–7) 3 (1–11) 0.001 1 (0–7) 2 (0–8) 3 (1–14) < 0.001
Cause of respiratory failure
 Pneumonia 170 (33.8) 49 (33.8) 46 (52.9) 0.004 211 (34.2) 62 (33.3) 97 (44.7) 0.013
 Extrapulmonary sepsis 104 (20.7) 30 (20.7) 10 (11.5) 0.095 111 (18.0) 38 (20.4) 31 (14.3) 0.343
 ARDS 40 (8.0) 15 (10.3) 9 (10.3) 0.326 50 (8.1) 14 (7.5) 27 (12.4) 0.087
 CPR 31 (6.2) 8 (5.5) 2 (2.3) 0.204 39 (6.3) 11 (5.9) 9 (4.1) 0.259
 Coma 23 (4.6) 8 (5.5) 6 (6.9) 0.396 35 (5.7) 10 (5.4) 14 (6.5) 0.725
 Pulmonary edema 45 (8.9) 10 (6.9) 1 (1.1) 0.014 48 (7.8) 9 (4.8) 4 (1.8) 0.001
 Ventilatory failure 28 (5.6) 9 (6.2) 2 (2.3) 0.409 34 (5.5) 11 (5.9) 6 (2.8) 0.159
 Central airway obstruction 14 (2.8) 2 (1.4) 3 (3.4) 1.000 30 (4.9) 9 (4.8) 5 (2.3) 0.143
 Exacerbation of ILD 12 (2.4) 3 (2.1) 2 (2.3) 1.000 13 (2.1) 4 (2.2) 4 (1.8) 0.894
 Others 36 (7.2) 11 (7.6) 6 (6.9) 1.000 46 (7.5) 18 (9.7) 20 (9.2) 0.332
SAPS III on ICU admission 61 (50–73) 63 (54–76) 64 (53–77) 0.046 61 (50–73) 63 (54–76) 65 (55–76) 0.001
SOFA score on ICU admission 8 (5–11) 8 (5–11) 8 (5–11) 0.514 8 (5–11) 8 (5–11) 9 (5–12) 0.063
Interval between hospital admission and intubation, days 1 (0–8) 2 (0–8) 3 (1–14) < 0.001 1 (0–8) 3 (1–10) 4 (1–16) < 0.001
  1. ICC International Consensus Conference, WIND Weaning according to a New Definition, ICU intensive care unit, ARDS acute respiratory distress syndrome, ILD interstitial lung disease, CPR cardiopulmonary resuscitation, SAPS III Simplified Acute Physiology Score III, SOFA Sequential Organ Failure Assessment
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