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Table 5 Clinical outcomes according to ICC and WIND classifications

From: Validation of a new WIND classification compared to ICC classification for weaning outcome

Variables ICC classification WIND classification
Simple
(n = 503)
Difficult
(n = 145)
Prolonged
(n = 87)
P for trend Group 1
(n = 617)
Group 2
(n = 186)
Group 3
(n = 217)
P for trend
Interval between intubation and the first SA, days 3 (2–5) 3 (2–6) 4 (2–7) 0.002 3 (2–5) 3 (2–6) 4 (2–9) < 0.001
SOFA score at the day of first SA 5 (3–7) 6 (3–8) 5 (4–8) < 0.001 5 (3–7) 6 (4–8) 7 (5–9) < 0.001
MV days 3 (2–6) 7 (4–10) 19 (12–28) < 0.001 3 (2–5) 7 (5–10) 21 (14–35) < 0.001
Ventilator-free daysa 25 (22–26) 21 (18–24) 0 (0–13) < 0.001 25 (23–26) 19 (0–23) 0 (0–5) < 0.001
Tracheostomy 40 (8.0) 37 (25.5) 62 (71.3) < 0.001 109 (17.7) 64 (34.4) 162 (74.7) < 0.001
 No 463 (92.0) 108 (74.5) 25 (28.7) 508 (82.3) 122 (65.6) 55 (25.3)
 Before MV 10 (1.6) 3 (1.6) 1 (0.5)
 Between MV and first SA 63 (10.2) 21 (11.3) 40 (18.4)
 Between first SA and extubation 12 (2.4) 25 (17.2) 60 (69.0) 0 32 (17.2) 119 (54.8)
 After the first extubation 28 (5.6) 12 (8.3) 2 (2.3) 36 (5.8) 8 (4.3) 2 (0.9)
Interval between intubation and tracheostomy, daysb 18 (13–33) 12 (5–19) 11 (9–15) < 0.001 10 (2–17) 7 (4–12) 12 (9–15) < 0.001
Successful weaning from MVc 486 (96.6) 138 (95.2) 40 (46.0) < 0.001 608 (98.5) 143 (76.9) 73 (33.6) < 0.001
ICU mortality 27 (5.4) 8 (5.5) 33 (37.9) < 0.001 22 (3.6) 31 (16.7) 92 (42.4) < 0.001
LOS in ICU, days 6 (3–9) 10 (6–14) 21 (14–30) < 0.001 6 (4–9) 10 (7–14) 24 (17–35) < 0.001
Hospital mortality 113 (22.5) 37 (25.5) 55 (63.2) < 0.001 131 (21.2) 63 (33.9) 134 (61.8) < 0.001
LOS in hospital, days 24 (14–45) 31 (19–57) 40 (27–74) < 0.001 25 (15–51) 29 (16–52) 45 (29–78) < 0.001
Type of discharge
 Home 296 (58.8) 72 (49.7) 10 (11.5) 343 (55.6) 62 (33.3) 17 (7.8)
 Other hospital 82 (16.3) 30 (20.7) 17 (19.5) 129 (20.9) 45 (24.2) 40 (18.4)
 Other ICU 0 1 (0.7) 3 (3.4) 0 4 (2.2) 10 (4.6)
 Hospice 12 (2.4) 5 (3.4) 2 (2.3) 14 (2.3) 12 (6.5) 16 (7.4)
 Death 113 (22.5) 37 (25.5) 55 (63.2) 131 (21.2) 63 (33.9) 134 (61.8)
  1. ICC International Consensus Conference, WIND Weaning according to a New Definition, SA separation attempt, SOFA Sequential Organ Failure Assessment, MV mechanical ventilation, ICU intensive care unit, LOS length of stay
  2. aVentilator-free days are defined as 28 minus the total number of days with invasive MV. Nonsurvivors were considered as having 0 ventilator-free days
  3. bExcluded patients with no tracheostomy and tracheostomy prior to mechanical ventilation
  4. cSuccessful weaning is defined as in the WIND Study (Intubated patients: extubation without death or reintubation within 7 days after extubation [whether postextubation noninvasive ventilation was used or not] or ICU discharge without invasive mechanical ventilation within 7 days, whichever comes first. Tracheostomized patients: spontaneous ventilation through tracheostomy without any mechanical ventilation during 7 consecutive days or ICU discharge with spontaneous breathing, whichever comes first)
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