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Table 5 Clinical outcomes according to ICC and WIND classifications

From: Validation of a new WIND classification compared to ICC classification for weaning outcome

Variables

ICC classification

WIND classification

Simple

(n = 503)

Difficult

(n = 145)

Prolonged

(n = 87)

P for trend

Group 1

(n = 617)

Group 2

(n = 186)

Group 3

(n = 217)

P for trend

Interval between intubation and the first SA, days

3 (2–5)

3 (2–6)

4 (2–7)

0.002

3 (2–5)

3 (2–6)

4 (2–9)

< 0.001

SOFA score at the day of first SA

5 (3–7)

6 (3–8)

5 (4–8)

< 0.001

5 (3–7)

6 (4–8)

7 (5–9)

< 0.001

MV days

3 (2–6)

7 (4–10)

19 (12–28)

< 0.001

3 (2–5)

7 (5–10)

21 (14–35)

< 0.001

Ventilator-free daysa

25 (22–26)

21 (18–24)

0 (0–13)

< 0.001

25 (23–26)

19 (0–23)

0 (0–5)

< 0.001

Tracheostomy

40 (8.0)

37 (25.5)

62 (71.3)

< 0.001

109 (17.7)

64 (34.4)

162 (74.7)

< 0.001

 No

463 (92.0)

108 (74.5)

25 (28.7)

508 (82.3)

122 (65.6)

55 (25.3)

 Before MV

10 (1.6)

3 (1.6)

1 (0.5)

 Between MV and first SA

63 (10.2)

21 (11.3)

40 (18.4)

 Between first SA and extubation

12 (2.4)

25 (17.2)

60 (69.0)

0

32 (17.2)

119 (54.8)

 After the first extubation

28 (5.6)

12 (8.3)

2 (2.3)

36 (5.8)

8 (4.3)

2 (0.9)

Interval between intubation and tracheostomy, daysb

18 (13–33)

12 (5–19)

11 (9–15)

< 0.001

10 (2–17)

7 (4–12)

12 (9–15)

< 0.001

Successful weaning from MVc

486 (96.6)

138 (95.2)

40 (46.0)

< 0.001

608 (98.5)

143 (76.9)

73 (33.6)

< 0.001

ICU mortality

27 (5.4)

8 (5.5)

33 (37.9)

< 0.001

22 (3.6)

31 (16.7)

92 (42.4)

< 0.001

LOS in ICU, days

6 (3–9)

10 (6–14)

21 (14–30)

< 0.001

6 (4–9)

10 (7–14)

24 (17–35)

< 0.001

Hospital mortality

113 (22.5)

37 (25.5)

55 (63.2)

< 0.001

131 (21.2)

63 (33.9)

134 (61.8)

< 0.001

LOS in hospital, days

24 (14–45)

31 (19–57)

40 (27–74)

< 0.001

25 (15–51)

29 (16–52)

45 (29–78)

< 0.001

Type of discharge

 Home

296 (58.8)

72 (49.7)

10 (11.5)

343 (55.6)

62 (33.3)

17 (7.8)

 Other hospital

82 (16.3)

30 (20.7)

17 (19.5)

129 (20.9)

45 (24.2)

40 (18.4)

 Other ICU

0

1 (0.7)

3 (3.4)

0

4 (2.2)

10 (4.6)

 Hospice

12 (2.4)

5 (3.4)

2 (2.3)

14 (2.3)

12 (6.5)

16 (7.4)

 Death

113 (22.5)

37 (25.5)

55 (63.2)

131 (21.2)

63 (33.9)

134 (61.8)

  1. ICC International Consensus Conference, WIND Weaning according to a New Definition, SA separation attempt, SOFA Sequential Organ Failure Assessment, MV mechanical ventilation, ICU intensive care unit, LOS length of stay
  2. aVentilator-free days are defined as 28 minus the total number of days with invasive MV. Nonsurvivors were considered as having 0 ventilator-free days
  3. bExcluded patients with no tracheostomy and tracheostomy prior to mechanical ventilation
  4. cSuccessful weaning is defined as in the WIND Study (Intubated patients: extubation without death or reintubation within 7 days after extubation [whether postextubation noninvasive ventilation was used or not] or ICU discharge without invasive mechanical ventilation within 7 days, whichever comes first. Tracheostomized patients: spontaneous ventilation through tracheostomy without any mechanical ventilation during 7 consecutive days or ICU discharge with spontaneous breathing, whichever comes first)