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Fig. 2 | Annals of Intensive Care

Fig. 2

From: Melatonin and cortisol exhibit different circadian rhythm profiles during septic shock depending on timing of onset: a prospective observational study

Fig. 2

Radar plots and longitudinal trends of aMT6s and cortisol urine excretion in patients who had septic shock at the time of ICU admission (Group A). a Radar plots of urinary aMT6s excretion mean values (ng) per 4-h intervals upon entry and exit and within a 24-h period in patients who had septic shock at the time of ICU admission (N = 15). The value 0 corresponds to midnight. The blue arrow indicates when urine collection began/ended for all patients. aMT6s = 6-sulfatoxymelatonin. b Longitudinal 24-h profiles of urinary melatonin excretion (aMT6s) mean values per 4-h intervals upon entry and exit in patients who had septic shock at the time of ICU admission. Error bars represent standard deviations (SDs). The value 0 on x axis corresponds to midnight. c Radar plots of urinary cortisol excretion mean values (ng) per 4-h intervals upon entry and exit and within a 24-h period in patients who had septic shock at the time of ICU admission. The value 0 corresponds to midnight. The blue arrow indicates when urine collection began/ended for all patients. d Longitudinal 24-h profiles of urinary cortisol excretion mean values per 4-h intervals upon entry and exit in patients who had septic shock at the time of ICU admission. Error bars represent standard deviations (SDs). The value 0 on x axis corresponds to midnight

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