Skip to main content

Table 1 Patients initial characteristics in the overall population and according to kidney disease: improving global outcomes definition at day 1

From: ICU survival and need of renal replacement therapy with respect to AKI duration in critically ill patients

Variable

All (n = 5242)

AKI stage 1 (n = 2458)

AKI stage 2 (n = 1181)

AKI stage 3 (n = 1603)

P value*

Patients characteristics

     

 Sex (male)

3176 (60.59)

1591 (64.73)

663 (56.14)

922 (57.52)

< .01

 Age (years)

70.2 [58.0–78.9]

70.5 [58.4–78.9]

72.5 [60.9–80.1]

68.0 [56.2–77.4]

< .01

 SAPS II

50 [37–67]

46 [35–61]

52 [39–69]

54 [41–72]

< .01

 SOFAa

5 [3, 10]

5 [3–8]

6 [3–8]

5 [3–9]

< .01

 Pulmonary insufficiency  immuno

651 (12.42)

373 (15.17)

147 (12.45)

131 (8.17)

< .01

 Suppression

946 (18.05)

389 (15.83)

223 (18.88)

334 (20.84)

< .01

AKI risk factors

     

 Cardiac insufficiency

961 (18.33)

434 (17.66)

247 (20.91)

280 (17.47)

0.03

 Cirrhosis

344 (6.56)

147 (5.98)

79 (6.69)

118 (7.36)

0.22

 Diabetes

1098 (20.95)

506 (20.59)

252 (21.34)

340 (21.21)

0.83

 Nephrotoxicb

1355 (25.85)

611 (24.86)

322 (27.27)

422 (26.33)

0.26

 Contrast agent

330 (6.30)

167 (6.79)

67 (5.67)

96 (5.99)

0.36

 Aminoside

954 (18.20)

421 (17.13)

235 (19.90)

298 (18.59)

0.11

 Glycopeptide

404 (7.71)

170 (6.92)

94 (7.96)

140 (8.73)

0.10

Reason for ICU admission

     

 Admission

    

< .01

 Medical

4031 (77.15)

1870 (76.23)

919 (78.21)

1242 (77.77)

 

 Emergency surgery

827 (15.83)

356 (14.51)

197 (16.77)

274 (17.16)

 

 Scheduled surgery

367 (7.02)

227 (9.25)

59 (5.02)

81 (5.07)

 

 Shock

2148 (40.98)

862 (35.07)

554 (46.91)

732 (45.66)

< .01

 ARF

1183 (22.57)

706 (28.72)

272 (23.03)

205 (12.79)

< .01

 Hospital stay before ICU admission (days)

0 [0;3]

0 [0;2]

0 [0;3]

0 [0;3]

0.81

Outcome

     

 AKI duration

2 [1–5]

2 [1–4]

2 [1–4]

3 [2–6]

< .01

 Day-28 renal recovery

3085 (58.85)

1613 (65.62)

741 (62.74)

731 (45.60)

< .01

 Day-28 mortality

1307 (24.93)

559 (22.74)

327 (27.69)

421 (26.26)

< .01

 Discharge alive at Day 28

3537 (67.47)

1704 (69.32)

769 (65.11)

1064 (66.38)

0.03

 RRT requirement during ICU stay

1336 (25.49)

275 (11.19)

179 (15.16)

882 (55.02)

< .01

  1. Qualitative variables are presented as frequency (and corresponding percentage), quantitative variables as median (interquartile range)
  2. KDIGO kidney disease: improving global outcomes; SAPS Simplified Acute Physiology Score; SOFA Sequential Organ Failure Assessment; AKI, Acute kidney injury; ICU, intensive care unit; ARF, Acute respiratory failure; RRT, Renal replacement therapy
  3. * Comparison between the three tested groups
  4. aExcept renal component
  5. bThe day of admission