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Table 4 Patient characteristics, stratified by history of hypertension (N = 233)

From: Impact of individualized target mean arterial pressure for septic shock resuscitation on the incidence of acute kidney injury: a retrospective cohort study

Characteristic

No hypertension (n = 80)

History of hypertension (n = 153)

p value

Age, median (IQR), year

62.5 (50.6–78.0)

74.5 (63.4–82.6)

.01

Body mass index, median (IQR), kg/m2

25.0 (21.2–28.7)

28.0 (23.3–33.6)

.01

Male sex, No. (%)

45 (56.3)

83 (54.2)

.78

Pre-admission MAP, median (IQR), mmHga

77.3 (72.1–87.3)

81.3 (75.0–90.5)

.13

Post-resuscitation MAP, median (IQR), mmHgb

68.0 (62.2–76.5)

68.0 (62.0–74.4)

.98

ΔMAP, median (IQR), mmHgc

11.3 (3.0–17.9)

12.7 (4.0–21.0)

.18

Acute kidney injury, No. (%)

45 (56.3)

115 (75.2)

.01

 Stage 1

25 (34.3)

48 (65.8)

 

 Stage 2

12 (22.2)

42 (77.8)

 

 Stage 3

8 (24.2)

25 (75.8)

 

Charlson comorbidity index, median (IQR)

5 (3–7)

8 (6–11)

.01

APACHE III score, 24 h, median (IQR)

71 (61.3–88.8)

86 (69.5–103)

.01

SOFA score, day 1, median (IQR)

6 (4–9)

7 (4–10)

.40

Any inotropic agent, No. (%)

8 (10.0)

24 (15.7)

.32

Any vasoactive agent, No. (%)

46 (57.5)

94 (61.4)

.58

Fluid balance, median (IQR), mL

6419 (3334–8953)

6073 (2398–10,225)

.43

  1. APACHE acute physiology, age, chronic health evaluation, MAP mean arterial pressure, SOFA Sequential organ failure assessment
  2. aFrom noninvasive blood pressure monitoring
  3. bSeventh hour of early goal-directed therapy
  4. cDefined as pre-admission minus post-resuscitation MAP