Fig. 2

Individual change in forced expiratory volume in one second. a Individual values of forced expiratory volume in one second are indicate before and after each procedure at the left and right of each panel, respectively. The thick line represents the median values of the population. b Relative changes in forced expiratory volume in one second were similar and not significantly different between Standard-nebulization and nasal high-flow nebulization, whereas changes were significantly lower when implementing nasal high-flow without nebulization. Standard-nebulization consisted in 2.5 mg albuterol delivery with a jet nebulizer connected to an aerosol facial mask, nasal high-flow nebulization consisted in 2.5 mg albuterol delivered within a nasal high-flow circuit, and Control-nasal high-flow consisted in nasal high-flow delivered without nebulization. NHF nasal high-flow, FEV₁ forced expiratory volume in one second