Comparison of the accuracy of neutrophil CD64, procalcitonin, and C-reactive protein for sepsis identification: a systematic review and meta-analysis

Annals of Intensive Care

Table 4 Results from individual studies of neutrophil CD64 and C-reactive protein as markers for the diagnosis of sepsis

References	Sepsis/control (n)	Neutrophil CD64			C-reactive protein
References	Sepsis/control (n)	Sensitivity	Specificity	AUC	Sensitivity	Specificity	AUC
Davis et al. [18]	38/62	0.88	0.71	–	0.88	0.59	–
Dimoula et al. [26]	103/365	0.89	0.87	0.94	0.84	0.86	0.92
Righi et al. [27]	61/32	0.90	0.97	0.93	0.89	0.41	0.71
Godnic et al. [28]	40/7	0.76	0.75	0.83	0.77	0.75	0.73
Bauer et al. [29]	110/86	0.76	0.77	0.83	0.77	0.77	0.86
Muzlovic et al. [30]	25/7	1.00	0.86	0.93	0.83	0.86	0.87
Total	377/559	0.84 (95% CI 0.76–0.89)	0.81 (95% CI 0.73–0.87)	0.89 (95% CI 0.87–0.92)	0.83 (95% CI 0.78–0.86)	0.71 (95% CI 0.56–0.85)	0.84 (95% CI 0.80–0.88)