Comparison of the accuracy of neutrophil CD64, procalcitonin, and C-reactive protein for sepsis identification: a systematic review and meta-analysis

Annals of Intensive Care

Table 5 Results from individual studies of neutrophil CD64 and procalcitonin as markers for the diagnosis of sepsis

References	Sepsis/control (n)	Neutrophil CD64			Procalcitonin
References	Sepsis/control (n)	Sensitivity	Specificity	AUC	Sensitivity	Specificity	AUC
Cardelli et al. [20]	52/60	0.96	0.95	0.97	0.94	0.70	–
Hsu et al. [21]	55/11	0.89	0.96	0.93	0.56	1.00	0.80
Gibot et al. [23]	154/146	0.84	0.95	0.95	0.83	0.85	0.91
Godnic et al. [28]	40/7	0.76	0.75	0.83	0.58	0.67	0.63
Bauer et al. [29]	110/86	0.76	0.77	0.83	0.73	0.74	0.82
Muzlovic et al. [30]	25/7	1.00	0.86	0.93	0.82	1.00	0.91
Total	436/317	0.83 (95% CI 0.76–0.88)	0.88 (95% CI 0.77–0.94)	0.89 (95% CI 0.84–0.95)	0.76 (95% CI 0.61–0.86)	0.79 (95% CI 0.70–0.86)	0.84 (95% CI 0.79–0.89)