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Table 4 Changes in ventilation and oxygenation parameters between baseline and after reduction in tidal volumes at 1 h

From: Low-flow CO2 removal in combination with renal replacement therapy effectively reduces ventilation requirements in hypercapnic patients: a pilot study

 

Baseline

+ 1 h

Δ (%)

P-value

VT/PBW (ml/kg)

6.2 ± 0.9

5.4 ± 1.1

− 0.8 (− 12.9)

< 0.05

RMV (l/min)

9.9 ± 2.1

8.5 ± 2.1

− 1.4 (− 14.1)

< 0.05

Pplat (cmH2O)

30.6 ± 4.6

27.7 ± 4.1

− 2.9 (− 9.5)

< 0.05

ΔP (cmH2O)

18.3 ± 4.3

15.6 ± 3.9

− 2.7 (− 14.8)

< 0.05

PaO2 (mmHg)

91.8 ± 23.8

84.4 ± 18.7

− 7.4 (− 8.1)

< 0.05

P/F (mmHg)

164 ± 38

151 ± 35

− 13 (− 7.9)

< 0.05

  1. VT tidal volume; PBW predicted body weight; RMV respiratory minute volume; Pplat plateau pressure; ΔP driving pressure; PaO2 arterial O2 partial pressure; P/F oxygenation index
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