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Table 3 Physiological characteristics of the patients—prospective phase (N = 30 patients)

From: Photoplethysmographic determination of the respiratory rate in acutely ill patients: validation of a new algorithm and implementation into a biomedical device

Physiological characteristics

 

 Age (mean ± SD)

61.4 ± 11.8

 Sex ratio (F/M)

11/19

 BMI (kg/m2; mean ± SD)

27.1 ± 7.0

 SAPS II (mean ± SD)

41.8 ± 16.8

 Chronic respiratory disorder n-(%)

10 (33.3)

 Immunodepression n-(%)

2 (6.7)

 Admission diagnosis

 

  Respiratory failure n-(%)

23 (76.7)

  Cardiovascular failure n-(%)

1 (3.3)

  Neurological failure n-(%)

3 (10.0)

  Other n-(%)

2 (6.6)

 ICU length of stay (day; mean ± SD)

16.3 ± 15.5

 Hospital length of stay (day; mean ± SD)

27.9 ± 20.8

 Overall survival rate n-(%)

22 (73.3)

Respiratory conditions

 Mechanical ventilation n-(%)

10 (33.3)

 Spontaneous ventilation n-(%)

20 (66.6)

 SpO2 (%; mean ± SD)

93.1 ± 2.5

 PaO2/FIO2 or SpO2/FIO2 (mean ± SD)

311 ± 79

 Sedation n-(%)

6 (20)

Hemodynamic conditions

 Heart rate (b/min; mean ± SD)

94.2 ± 18.9

 Mean arterial blood pressure (mmHg; mean ± SD)

87.2 ± 19.2

 Atrial fibrillation

0 (0)

 Vasopressive agents n-(%)

5 (16.7)

 Hemodynamic instability n-(%)

2 (6.7)

Number of patients with reference values

 RR-Manual (reference) n-(%)

30/30 (100)

 RR-ECG n-(%)

28/30 (93.3)

 RR-PPG n-(%)

30/30 (100)

Measurements

 Reference RR (c/min)

22 ± 4

 Estimated RR-PPG (c/min)

22 ± 5

 Estimated RR-ECG (c/min)

23 ± 6

  1. Values are provided as n-(%) or mean ± SD, unless specified otherwise
  2. Reference RR values are provided as the chronometric measurement measured over 30 s under spontaneous ventilation or as the ventilatory rate for patients under ventilatory assistance
  3. Chronic respiratory disorders are considered for a previous medical history of COPD, OSA and chronic respiratory insufficiency
  4. Oxygenation parameters are provided as PaO2/FIO2 for patients under mechanical ventilation or as SpO2/FIO2 for patients under spontaneous ventilation
  5. Hemodynamic instability was defined as a need for fluid challenge (≥ 500 mL) and/or vasopressive agent increase during the past 2 h of care
  6. BMI, body mass index; SAPS II, Simplified Acute Physiology Score version 2; ICU, intensive care unit; SpO2, pulse oximetry saturation; PaO2, partial pressure of oxygen in arterial blood; FIO2, inspiratory fraction of oxygen; IV, intravenous; PEEP, positive end-expiratory pressure; RR-Manual, chronometric measurement of the respiratory rate; RR-PPG, estimated respiratory rate using the plethysmographic curve analysis; RR-ECG, evaluation of the respiratory rate on the electrocardiogram, using electrical impedance