Skip to main content

Table 2 Infectious complications and outcomes in heart transplant recipients within 180 days after heart transplantation

From: Infectious complications following heart transplantation in the era of high-priority allocation and extracorporeal membrane oxygenation

Events Overall population (n = 113)
Deaths; n (%) 19 (17)
Patients with ≥ 1 post-transplant infection(s) of all pathogens; n (%) 92 (81)
Number of post-transplant non-viral infectious episodes 181
Site of non-viral infections; n (% infectious episodes)a  
 Respiratory tract 95 (52)
 Skin and soft tissues 26 (14)
 Urinary tract 22 (12)
 Bloodstream infection of unknown origin 18 (10)
 Secondary bloodstream infections 12 (7)
 Mediastinitis 11 (6)
 Catheter-related infection 8 (4)
 Otherb 13 (7)
Patients with at least an infection caused by; n (%)c  
Overall bacteria and fungi 80 (71)
Gram-negative bacilli 63 (56)
Enterobacteriaceae 50 (44)
P. aeruginosa 24 (21)
Gram-positive cocci 35 (31)
S. aureus 4 (3)
Enterococci 19 (17)
Streptococci 10 (9)
Multi-drug-resistant bacteria 21 (19)
Fungi 16 (14)
Candida spp. 4 (4)
Aspergillus spp. 6 (5)
Otherd 6 (5)
Patients with a viral infection; n (%) 44 (39)
 CMV infection 39 (34)
 HSV infection 10 (9)
Patients with treated acute rejection; n (%) 24 (21)
  1. Multi-drug-resistant bacteria: lack of susceptibility to one or more agents in three or more antimicrobial categories active against the isolated bacteria
  2. CMV cytomegalovirus, HSV herpes simplex virus
  3. aOne episode could be counted multiple times according to the number of infectious sites
  4. bOther infections: 8 gastrointestinal tract infections, 2 central nervous system infections and 3 other infections
  5. cA same patient could have been infected by different germs during the same period
  6. dOther invasive fungal infections: (Fusarium spp. n = 1, Pneumocystis jiroveci n = 1, Microsporidium spp. n = 1, Trichosporon spp. n = 1, undefined yeast n = 2)