TY - JOUR AU - de Jager, Pauline AU - Kamp, Tamara AU - Dijkstra, Sandra K. AU - Burgerhof, Johannes G. M. AU - Markhorst, Dick G. AU - Curley, Martha A. Q. AU - Cheifetz, Ira M. AU - Kneyber, Martin C. J. PY - 2019 DA - 2019/01/18 TI - Feasibility of an alternative, physiologic, individualized open-lung approach to high-frequency oscillatory ventilation in children JO - Annals of Intensive Care SP - 9 VL - 9 IS - 1 AB - High-frequency oscillatory ventilation (HFOV) is a common but unproven management strategy in paediatric critical care. Oscillator settings have been traditionally guided by patient age and/or weight rather than by lung mechanics, thereby potentially negating any beneficial effects. We have adopted an open-lung HFOV strategy based on a corner frequency approach using an initial incremental–decremental mean airway pressure titration manoeuvre, a high frequency (8–15 Hz), and high power to initially target a proximal pressure amplitude (∆Pproximal) of 70–90 cm H2O, irrespective of age or weight. SN - 2110-5820 UR - https://doi.org/10.1186/s13613-019-0492-0 DO - 10.1186/s13613-019-0492-0 ID - de Jager2019 ER -