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Table 3 Factors associated with VA-ECMO weaning after propensity score matching

From: Impact of levosimendan on weaning from peripheral venoarterial extracorporeal membrane oxygenation in intensive care unit

Variables Success (n = 73) Failure (n = 30) P-value
Length of stay in hospital before VA-ECMO (day) 5.6 ± 8.5 3.9 ± 9.1 0.35
Length of stay in ICU before VA-ECMO (day) 1.4 ± 5.1 0.7 ± 1.1 0.19
Clinical characteristics at ICU admission
 Simplified Acute Physiology Score 2 56.6 ± 19.0 62.1 ± 18.2 0.18
 Male 50 (68.5) 22 (73.3) 0.63
 Age (years) 52.5 ± 15.8 57.9 ± 11.1 0.09
 Body mass index > 30 kg/m2 13 (17.8) 8 (26.7) 0.31
 Previous coronary artery disease 22 (30.1) 12 (40.0) 0.33
 Hypertension 27 (37.0) 17 (56.7) 0.07
 Chronic renal failure with dialysis 10 (13.7) 4 (13.3) 1.00
 Chronic obstructive pulmonary disease 4 (5.5) 4 (13.3) 0.23
 Diabetes mellitus 23 (31.5) 15 (50.0) 0.08
 History of congestive heart failure 18 (24.7) 4 (13.3) 0.2
 Immunosuppression 2 (2.7) 0 (0.0) 1.0
 Liver cirrhosis 2 (2.7) 0 (0.0) 1.00
 Cancer 0 0 1
 Smoking (current or former) 24 (32.9) 12 (40.0) 0.49
 Hazardous alcohol use 14 (19.2) 7 (23.3) 0.63
 Glasgow Coma Scale score 13.6 ± 3.8 13.3 ± 4.1 0.73
 Catecholamines 72 (98.6) 30 (100.0) 1.00
 Mechanical ventilation 65 (89.0) 28 (93.3) 0.72
 Renal replacement therapy 31 (42.5) 15 (50.0) 0.48
 Total bilirubin level (µmol/L) 35.9 ± 44.2 28.0 ± 37.8 0.39
 Platelet count (G/L) 152.3 ± 102.8 157.1 ± 96.2 0.82
 Prothrombin (%) 49.3 ± 21.4 43.3 ± 17.2 0.18
 Hemoglobin level (g/dL) 10.9 ± 10.6 9.9 ± 2.1 0.59
 Creatinine level (µmol/L) 173.8 ± 138.4 201.4 ± 201.5 0.43
 Left ventricular ejection fraction (%) 20.2 ± 6.5 20.3 ± 7.4 0.97
Reason for VA-ECMO    0.28
 Cardiac arrest 1 (1.4) 2 (6.7)  
 Dilated cardiomyopathy 8 (11.0) 1 (3.3)  
 Myocarditis 5 (6.8) 0 (0.0)  
 Acute myocardial infarction 20 (27.4) 11 (36.7)  
 Post-cardiotomy 28 (38.4) 10 (33.3)  
 Other reason 11 (15.1) 6 (20.0)  
 Percutaneous implantation of VA-ECMO 34 (46.6) 11 (36.7) 0.36
Hemodynamic parameters (first 24 h post-VA-ECMO)
 VA-ECMO flow (L/min) 3.5 ± 0.6 3.6 ± 0.5 0.51
 Maximal dose of norepinephrine (µg/kg/min) 0.8 ± 0.6 0.6 ± 0.6 0.15
 Maximal dose of dobutamine (µg/kg/min) 10.1 ± 3.7 10.4 ± 4.5 0.69
 Intra-aortic balloon pump 24 (32.9) 8 (26.7) 0.54
VA-ECMO duration 11.9 ± 8.8 9.3 ± 5.4 0.14
Levosimendan 32 (43.8) 6 (20.0) 0.01
  1. Results are expressed as mean ± SD or number (%)
  2. VA-ECMO venoarterial extracorporeal membrane oxygenation, ICU intensive care unit