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Fig. 5 | Annals of Intensive Care

Fig. 5

From: Effects of chloride content of intravenous crystalloid solutions in critically ill adult patients: a meta-analysis with trial sequential analysis of randomized trials

Fig. 5

Trial sequential analysis for in-hospital mortality in subgroup of septic patients. A relative risk reduction relative risk reduction of 14.48% according to the in-hospital mortality in balanced crystalloids group (24.8%) and the control group (29%) was pursued. The cumulated Z-curve (blue) crossed the conventional boundary, but did not exceed either the trial sequential monitoring boundary for benefit or the required information size of 4686

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