|
Crystalloid fluid type
|
|
LR [20,21,22]
|
3
|
150
|
1.00 [0.07, 15.33]
|
1.00
|
NA
|
|
Plasma-Lyte [9, 23, 24]
|
3
|
2375
|
0.91 [0.70, 1.19]
|
0.50
|
0
|
|
Mixed of LR and Plasma-Lyte [10, 25]
|
2
|
16776
|
0.93 [0.85, 1.01]
|
0.08
|
0
|
|
Test for subgroup differences: χ2 = 0.01, df = 2 (p = 0.99)
|
|
Crystalloid fluid volume
|
|
Median or mean volume more than 5L [20, 21, 23]
|
3
|
142
|
0.86 [0.25, 2.94]
|
0.80
|
0
|
|
Median or mean volume less than 5L [9, 10, 24, 25]
|
4
|
19105
|
0.92 [0.85,1.00]
|
0.06
|
0
|
|
Unclear [22]
|
1
|
54
|
NA
|
NA
|
NA
|
|
Test for subgroup differences: χ2 = 0.01, df = 1 (p = 0.90)
|
|
Setting
|
|
ICU [9, 10, 22,23,24,25]
|
6
|
19205
|
0.92 [0.85,1.00]
|
0.06
|
0
|
|
Transferred to ICU in perioperative period [20, 21]
|
2
|
96
|
1.00 [0.07, 15.33]
|
1.0
|
NA
|
|
Test for subgroup differences: χ2 = 0.00, df = 1 (p = 0.95)
|
|
Specific patients
|
|
Sepsis
|
|
Yes [9, 10]
|
2
|
2420
|
0.86 [0.75, 0.98]
|
0.02
|
0
|
|
No [9, 10, 20,21,22]
|
5
|
15794
|
0.96 [0.86, 1.07]
|
0.48
|
0
|
|
Classification not mentioned [23,24,25]
|
3
|
1087
|
0.95 [0.66, 1.37]
|
0.79
|
0
|
|
Test for subgroup differences: χ2 = 1.8, df = 2 (p = 0.41)
|
|
TBI
|
|
Yes [9, 10]
|
2
|
1420
|
1.11 [0.86, 1.43]
|
0.43
|
0
|
|
No [9, 10, 20,21,22]
|
5
|
16794
|
0.90 [0.82, 0.99]
|
0.02
|
0
|
|
Classification not mentioned [23,24,25]
|
3
|
1087
|
0.95 [0.66, 1.37]
|
0.79
|
0
|
|
Test for subgroup differences: χ2 = 2.31, df = 2 (p = 0.32)
|
|
Risk of bias
| | | | | |
|
High [10, 23, 25]
|
3
|
16822
|
0.92 [0.85, 1.01]
|
0.98
|
0
|
|
Low [9, 20, 22, 24]
|
4
|
2449
|
0.91 [0.69, 1.20]
|
0.42
|
0
|
|
Unclear [21]
|
1
|
30
|
NA
|
NA
|
NA
|
|
Test for subgroup differences: χ2 = 0.01, df = 1 (p = 0.93)
|
|
Including sample size (in each group)
|
|
Over 1000 [9, 10]
|
2
|
18064
|
0.92 [0.85, 1.00]
|
0.06
|
0
|
|
Equal or less than 1000 [20,21,22,23,24,25]
|
6
|
1237
|
0.95 [0.71, 1.28]
|
0.75
|
0
|
|
Test for subgroup differences: χ2 = 0.05, df = 1 (p = 0.82)
|
