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Annals of Intensive Care

Table 3 Multivariate logistic regression analysis for the association with ICU and hospital mortality in all included patients (n = 3966)

From: The association of intravenous insulin and glucose infusion with intensive care unit and hospital mortality: a retrospective study

Variable

ICU mortality (n = 309)

Hospital mortality (n = 455)

Adjusted OR (95% CI)

p value

Adjusted OR (95% CI)

p value

Age (per 10 years)

1.21 (1.07, 1.36)

0.002

1.38 (1.25, 1.52)

< 0.001

Cardiothoracic surgery patients

0.61 (0.39, 0.96)

0.032

0.34 (0.23, 0.49)

< 0.001

APACHE IV PM (per %)

1.02 (1.01, 1.03)

< 0.001

1.02 (1.01, 1.03)

< 0.001

Maximum SOFA score (per point)

1.26 (1.19, 1.34)

< 0.001

1.18 (1.13, 1.24)

< 0.001

Average sodium > 145 mmol/L

2.09 (1.29, 3.40)

0.003

2.17 (1.44, 3.27)

< 0.001

Daily intake (from all sources, per 100 kcal)

0.92 (0.89, 0.95)

< 0.001

0.94 (0.91, 0.97)

< 0.001

Mean BG (per mmol/L)

0.83 (0.70, 0.99)

0.040

0.76 (0.66, 0.88)

< 0.001

Percentage BG < 4.4 mmol/L (per %)

1.02 (1.00, 1.05)

0.089

1.02 (1.00, 1.05)

0.050

IV insulin per kg per day (per 0.1 IU)

1.09 (1.05, 1.13)

< 0.001

1.09 (1.06, 1.13)

< 0.001

IV glucose per day (per g increase)

1.01 (1.00, 1.01)

0.021

1.00 (1.00, 1.01)

0.094

Fluid balance (per L increase)

1.11 (1.08, 1.13)

< 0.001

1.08 (1.06, 1.11)

< 0.001

  1. For categorical variables, ‘no’ was used as reference category
  2. APACHE Acute Physiology and Chronic Health Evaluation, BG blood glucose, BMI body mass index, CI confidence interval, ICU intensive care unit, IU international unit, IV intravenous, MAG mean absolute glucose, OR odds ratio
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