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Table 1 Patient characteristics at ICU admission

From: Gender and survival of critically ill patients: results from the FROG-ICU study

Patient characteristics All N = 2087 Women N = 726 Men N = 1361 P value*
Demographic data     
 Age (year) 63 [51; 74] 63 [51; 74.8] 63 [51; 74] 0.59
 Body Mass Index (kg/m2) 26.5 [23.1; 30.8] 26 [22.5; 31.2] 26.6 [23.5; 30.3] 0.51
Comorbidities     
 Hypertension 902 (43.3%) 319 (43.9%) 583 (43%) 0.67
 Dyslipidaemia 412 (19.8%) 123 (16.9%) 289 (21.3%) 0.017
 Diabetes melllitus 384 (18.4%) 121 (16.7%) 263 (19.4%) 0.13
 Coronary artery disease 188 (9%) 35 (4.8%) 153 (11.3%) < 0.001
 Valvular heart disease (severe) 82 (3.9%) 31 (4.3%) 51 (3.8%) 0.57
 Heart failure 153 (7.3%) 57 (7.9%) 96 (7.1%) 0.52
 Peripheral vascular disease 209 (10%) 60 (8.3%) 149 (11%) 0.05
 Prior stroke 92 (4.4%) 25 (3.4%) 67 (4.9%) 0.11
 COPD 273 (13.1%) 70 (9.6%) 203 (15%) 0.001
 Chronic kidney disease 241 (11.6%) 80 (11%) 161 (11.9%) 0.57
 Chronic liver disease 158 (7.6%) 52 (7.2%) 106 (7.8%) 0.59
 Active malignant tumors 281 (13.5%) 93 (12.8%) 188 (13.9%) 0.51
 HIV 53 (2.5%) 12 (1.7%) 41 (3%) 0.06
 Loss of autonomy 78 (3.7%) 38 (5.2%) 40 (2.9%) 0.009
 Cognitive dysfunction 33 (1.6%) 13 (1.8%) 20 (1.5%) 0.58
Diagnosis at ICU admission     
 Respiratory disorder 89 (4.3%) 21 (2.9%) 68 (5%) 0.017
 Trauma 536 (25.7%) 182 (25.1%) 354 (26%)
 Sepsis/septic shock 179 (8.6%) 53 (7.3%) 126 (9.3%)
 Neurological disease 286 (13.7%) 120 (16.5%) 166 (12.2%)
 Cardiac arrest 394 (18.9%) 142 (19.6%) 252 (18.5%)
 Cardiogenic shock 146 (7%) 55 (7.6%) 91 (6.7%)
 Hemorrhagic shock 110 (5.3%) 31 (4.3%) 79 (5.8%)
 Planned surgery 165 (7.9%) 52 (7.2%) 113 (8.3%)
 Others 181 (8.7%) 70 (9.6%) 111 (8.2%)
Vital parameters     
 Temperature (°C) 37.2 [36.7; 37.8] 37.2 [36.7; 37.7] 37.3 [36.8; 37.9] 0.001
 Mean blood pressure (mmHg) 81.3 [72.3; 92] 81.3 [72.3; 91.7] 81.2 [72.3; 92] 0.81
 Heart rate (bpm) 92 [78; 106] 92 [79; 106] 91 [77; 106] 0.60
 Glasgow coma scale 14 [5; 15] 14 [4; 15] 14 [5; 15] 0.18
Laboratory values at admission     
 Arterial pH 7.4 [7.4; 7.5] 7.4 [7.4; 7.5] 7.4 [7.4; 7.5] 0.12
 Lactate (mmol/L) 1.4 [1; 2] 1.4 [1.1; 2] 1.4 [1; 1.9] 0.09
 Leukocytes (G/L) 10.9 [7.6; 16.2] 11.6 [8.2; 17] 10.6 [7.4; 15.8] 0.004
 Hemoglobin (g/L) 100 [89; 114] 99 [88; 109] 101 [90; 117] < 0.001
 Platelets (G/L) 164 [99; 244] 171 [98; 257] 162 [101; 237] 0.15
 BUN or Urea (mg/dL) 8.4 [5.2; 14] 7.1 [4.4; 12.6] 9.1 [5.6; 14.8] < 0.001
 Creatinine (mg/dL) 84 [59; 150] 69 [50; 119] 94 [66; 165] < 0.001
 Bilirubin (umol/L) 13 [8; 27] 11 [7; 21] 14 [9; 29] < 0.001
Organ support     
 Vasopressors at admission 1502 (72.2%) 526 (72.5%) 976 (72%) 0.84
 Ventilation during ICU stay:     
 Invasive 1632 (80.3%) 561 (79.7%) 1071 (80.6%) 0.76
 Non-invasive 316 (15.6%) 115 (16.3%) 201 (15.1%)
 RRT during ICU stay 480 (23%) 137 (18.9%) 343 (25.2%) 0.001
Disease severity scores     
 Charlson score 3 [1; 5] 3 [1; 5] 3 [1; 5] 0.15
 SAPS II 49 [36; 63] 50 [35; 62] 48 [36; 63] 0.85
 SOFA score 8 [5; 10] 7 [5; 10] 8 [5; 11] 0.12
  1. Data presented as median [interquartile range] and P value obtained with Mann–Whitney U-test for continuous variables and as number (percentage) with Fisher’s exact test for categorical variables