Skip to main content

Advertisement

Table 3 Characteristics of ICU-acquired infections

From: Pulmonary infections prime the development of subsequent ICU-acquired pneumonia in septic shock

Variables Pulmonary ICU-AI (n = 139) Non-pulmonary ICU-AI (n = 110) p
Time from admission to ICU-AI (days) 7 (5–11) 8 (5–12) 0.57
Sources of non-pulmonary ICU-AI
 Catheter 47 (43)  
 Abdominal 34 (31)  
 Skin and soft tissue 15 (14)  
 Urinary 5 (4)  
 Miscellaneous 3 (3)  
 Unknown 6 (5)  
Microbiological documentation 112 (80) 85 (77) 0.10
Positive blood culture 11 (8) 61 (55) <  0.001
Distribution of pathogens    < 0.001
 Gram-negative bacteria
  Pseudomonas aeruginosa 39 (28) 10 (9)  
  Escherichia coli 18 (13) 3 (2)  
  Enterobacter spp. 15 (11) 13 (12)  
  Klebsiella spp. 13 (9) 7 (6)  
  Serratia marcescens 7 (5) 0 (0)  
  Miscellaneous 7 (5) 1 (1)  
 Gram-positive bacteria
  Staphylococcus aureus 6 (4) 8 (7)  
  Enterococcus spp. 1 (1) 11 (10)  
  Miscellaneous 2 (2) 20 (19)  
 Fungi  
  Candida albicans 0 (0) 3 (2)
  Non-albicans Candida 0 (0) 6 (5)
  Aspergillus fumigatus 2 (1) 0 (0)
  Miscellaneous 2 (2) 0 (0)
 Virus
  Cytomegalovirus 0 (0) 3 (2)
Further episodes of ICU-AI 0.08
 None 85 (61) 72 (65)  
 1 episode 25 (18) 26 (24)  
 ≥ 2 episodes 29 (21) 12 (11)  
  1. Variables are expressed as median (interquartile range) or number (percentage), as appropriate
  2. ICU intensive care unit, ICU-AI intensive care unit-acquired infections, MRSA methicillin-resistant Staphylococcus aureus, MSSA methicillin-susceptible Staphylococcus aureus, GNB gram-negative bacteria