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Table 2 CT scan fibrosis scores according to lung fibroproliferation (NT-PCP-III > 9µG/L)

From: Chest CT scan and alveolar procollagen III to predict lung fibroproliferation in acute respiratory distress syndrome

 

No lung fibroproliferation (n = 175)

(NT-PCP-III ≤ 9 µG/L)

Lung fibroproliferation (n = 53)

(NT-PCP-III > 9 µG/L)

p value

Crude fibrosis score

12 [9–17]

14 [11–21]

0.002

 Ground glass

7 [5–12]

9 [6–14]

0.007

 Honeycombing

4 [4–5]

5 [3–5]

0.015

Corrected fibrosis score

2.8 [2.2–4.0]

3.4 [2.5–4.7]

< 0.001

 Ground glass

1.8 [1.2–3.0]

2.3 [1.5–3.3]

0.003

 Honeycombing

1 [1–1]

1 [1–1]

< 0.001

  1. Values are expressed as median [IQR]. NT-PCP-III: N-terminal peptide for type III procollagen. Each lobe of the lung was scored on a scale of 0–5 points for both ground glass and honeycombing abnormality. In the case of lobectomy or when consolidation was observed in more than 75% of a lobe, the score was not used for this lobe. The CT scan crude fibrosis score was calculated as the sum of points obtained for each lobe. We corrected the score by reporting it to the number of lobes evaluated (corrected fibrosis score = crude fibrosis score/number of lobes evaluated)
  2. p values were calculated by linear mixed model