Determinants of Doppler-based renal resistive index in patients with septic shock: impact of hemodynamic parameters, acute kidney injury and predisposing factors

Annals of Intensive Care

Table 2 Linear mixed model for predicting resistive index (RI) measured from day 1 (D1) to day 10 (D10)

RI from D1 to D10	Coefficient	95% CI	p
Fixed effects
MAP (+ 1 mmHg) if no chronic arterial hypertension and no diabetes	− 0.002	− 0.002; − 0.001	< 0.001
MAP (+ 1 mmHg) if chronic arterial hypertension and/or diabetes	− 0.001	− 0.002; − 0.001	< 0.001*
PP (+ 1 mmHg)	0.002	0.001; 0.002	< 0.001
Severe AKI at D3	0.032	0.006; 0.059	0.017
Recovery of severe AKI at day of RI measurement	− 0.030	− 0.057; − 0.003	0.031
Time (+ 1 day of ICU hospitalization)	0.003	0.001; 0.005	0.002
Constant	0.699	0.666; 0.733	< 0.001
Random effects	0.046	0.043; 0.050

All the continuous covariates, the coefficient associated with the considered covariate corresponds to the impact on renal resistive index of the increase of one unit in this covariate
MAP mean arterial pressure, PP pulse pressure, AKI acute kidney injury, ICU intensive care unit, Severe AKI acute kidney injury acute kidney injury network 2 or 3
*Interaction between MAP and chronic arterial hypertension and/or diabetes, p = 0.06