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Annals of Intensive Care

Table 1 Evolution of ventriculo-arterial coupling and left ventricular mechanical efficiency during different experimental stages

From: Determinants of left ventricular ejection fraction and a novel method to improve its assessment of myocardial contractility

 

VAC (a.u.)

LV efficiency (%)

 

Before

After

Before

After

Afterload

 Phenylephrine

2.06 ± 0.51

2.36 ± 0.51*

61 ± 9

55 ± 10*

 Nitroprusside

2.00 ± 0.49

1.42 ± 0.44†

61 ± 10

72 ± 11‡

Preload

 Bleeding

2.02 ± 0.61

1.57 ± 0.51*

58 ± 11

67 ± 11†

 Fluid bolus

1.72 ± 0.63

2.06 ± 0.73*

65 ± 12

57 ± 12*

Contractility

 Esmolol

1.50 ± 0.36

2.43 ± 0.61†

68 ± 7

47 ± 3‡

 Dobutamine

1.71 ± 0.47

1.14 ± 0.34‡

65 ± 7

75 ± 1‡

  1. Data are presented as mean ± SD
  2. A.u. arbitrary units, VAC ventriculo-arterial coupling, LVeff left ventricular mechanical efficiency
  3. *p < 0.05, †p ≤ 0.001 ,‡p ≤ 0.0001 versus “before” stage
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