Annals of Intensive Care

Table 2 Evolution of left ventricular diastolic function variables

From: Determinants of left ventricular ejection fraction and a novel method to improve its assessment of myocardial contractility

	τ (tau) (ms)		LV stiffness (β)
	Before	After	Before	After
Afterload
Phenylephrine	29.3 ± 2.9	33.5 ± 3.24^†	0.013 ± 0.003	0.014 ± 0.003*
Nitroprusside	27.4 ± 3.4	22.4 ± 2.2^‡	0.013 ± 0.003	0.012 ± 0.003^†
Preload
Bleeding	27.5 ± 3.5	22.8 ± 3.2^‡	0.012 ± 0.003	0.012 ± 0.003
Fluid bolus	25.4 ± 4.3	28.9 ± 4.1^†	0.012 ± 0.003	0.011 ± 0.002*
Contractility
Esmolol	27 ± 3.8	35 ± 5.4*	0.013 ± 0.002	0.012 ± 0.003
Dobutamine	27.1 ± 4	24.4 ± 4.5*	0.012 ± 0.002	0.012 ± 0.002

Data are presented as mean ± SD
τ (tau) time constant of the isovolumetric LV pressure relaxation, β LV chamber stiffness constant obtained from the end-diastolic pressure–volume relationship
*p < 0.05, ^†p ≤ 0.001 ,^‡p ≤ 0.0001 versus before stage

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