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Table 1 Baseline characteristics of the patients

From: Effects of mean arterial pressure on arousal in sedated ventilated patients with septic shock: a SEPSISPAM post hoc exploratory study

Characteristics at baseline Low-target group N = 253 (47.6%) High-target group N = 279 (52.4%) P
Age (years); mean ± SD 66 ± 14 65 ± 13 0.38
Simplified Acute Physiology Score II; mean ± SD 59.0 ± 15.4 57.2 ± 15.8 0.19
Sequential Organ Failure Assessment Score; mean ± SD 11.06 ± 3.1 11.0 ± 3.1 0.83
Male sex; n (%) 168 (66.4) 196 (70.3) 0.34
Preexisting medical conditions; n (%)
 Ischemic heart disease 31 (12.3) 28 (10) 0.426
 Chronic heart failure 36 (14.2) 42 (15.1) 0.79
 Chronic obstructive pulmonary disease 32 (12.6) 39 (14) 0.65
 Chronic renal failure 21 (8.3) 7 (2.5) 0.003
 Liver cirrhosis 13 (5.1) 18 (6.5) 0.52
 Diabetes 59 (23.3) 51/278 (18.3) 0.16
 Cancer or autoimmune disease 81 (32) 100 (35.8) 0.35
 Chronic arterial hypertension 112 (44.3) 120 (43) 0.77
Source of infection; n (%)
 Lung 142/249 (57) 156/275 (56.7) 0.95
 Abdomen 45/249 (18.1) 48/275 (17.5) 0.85
 Urinary tract 18/249 (7.2) 25/275 (9.1) 0.44
 Other 44/249 (17.7) 46/275 (16.7) 0.78
Hemodynamic and biochemical variables; mean ± SD
 Mean arterial pressure (mmHg)/n 74 ± 14 73 ± 14 0.38
 Arterial pH/n 7.27 ± 0.14 7.28 ± 0.12 0.45
 Serum lactate (mmol/L)/n 3.84 ± 3.85 3.31 ± 3.26 0.10
 Fluid therapy before inclusion (mL) 2993 ± 1405 3068 ± 1378 0.55
Acute kidney injury, n (%)a 86 (34) 77 (27.6) 0.11
  1. aAcute kidney injury was defined as plasma creatinine level > 1.9 mg/dL or urinary output, < 500 ml per day