TY - JOUR AU - Smith, L. S. AU - Zimmerman, J. J. AU - Martin, T. R. PY - 2013 DA - 2013// TI - Mechanisms of acute respiratory distress syndrome in children and adults: a review and suggestions for future research JO - Pediatr Crit Care Med VL - 14 UR - https://doi.org/10.1097/PCC.0b013e318291753f DO - 10.1097/PCC.0b013e318291753f ID - Smith2013 ER - TY - JOUR AU - Schouten, L. R. A. AU - Schultz, M. J. AU - Kaam, A. H. AU - Juffermans, N. P. AU - Bos, A. P. AU - Wösten-van Asperen, R. M. PY - 2015 DA - 2015// TI - Association between maturation and aging and pulmonary responses in animal models of lung injury:a systematic review JO - Anesthesiology VL - 123 UR - https://doi.org/10.1097/ALN.0000000000000687 DO - 10.1097/ALN.0000000000000687 ID - Schouten2015 ER - TY - JOUR AU - Xie, X. AU - Chen, J. AU - Wang, X. AU - Zhang, F. AU - Liu, Y. PY - 2006 DA - 2006// TI - Age- and gender-related difference of ACE2 expression in rat lung JO - Life Sci VL - 78 UR - https://doi.org/10.1016/j.lfs.2005.09.038 DO - 10.1016/j.lfs.2005.09.038 ID - Xie2006 ER - TY - JOUR AU - Kuba, K. AU - Imai, Y. AU - Rao, S. AU - Jiang, C. AU - Penninger, J. M. PY - 2006 DA - 2006// TI - Lessons from SARS: control of acute lung failure by the SARS receptor ACE2 JO - J Mol Med (Berl) VL - 84 UR - https://doi.org/10.1007/s00109-006-0094-9 DO - 10.1007/s00109-006-0094-9 ID - Kuba2006 ER - TY - JOUR AU - Imai, Y. AU - Kuba, K. AU - Rao, S. AU - Huan, Y. AU - Guo, F. AU - Guan, B. PY - 2005 DA - 2005// TI - Angiotensin-converting enzyme 2 protects from severe acute lung failure JO - Nature VL - 436 UR - https://doi.org/10.1038/nature03712 DO - 10.1038/nature03712 ID - Imai2005 ER - TY - JOUR AU - Schouten, L. R. A. AU - Helmerhorst, H. J. F. AU - Wagenaar, G. T. M. AU - Haltenhof, T. AU - Lutter, R. AU - Roelofs, J. J. PY - 2016 DA - 2016// TI - Age-dependent changes in the pulmonary renin-angiotensin system are associated with severity of lung injury in a model of acute lung injury in rats JO - Crit Care Med VL - 44 UR - https://doi.org/10.1097/CCM.0000000000002008 DO - 10.1097/CCM.0000000000002008 ID - Schouten2016 ER - TY - JOUR AU - Vught, L. A. AU - Klein Klouwenberg, P. M. C. AU - Spitoni, C. AU - Scicluna, B. P. AU - Wiewel, M. A. AU - Horn, J. PY - 2016 DA - 2016// TI - Incidence, risk factors, and attributable mortality of secondary infections in the intensive care unit after admission for sepsis JO - JAMA VL - 315 UR - https://doi.org/10.1001/jama.2016.2691 DO - 10.1001/jama.2016.2691 ID - Vught2016 ER - TY - JOUR AU - Scicluna, B. P. AU - Klein Klouwenberg, P. M. C. AU - Vught, L. A. AU - Wiewel, M. A. AU - Ong, D. S. AU - Zwinderman, A. H. PY - 2015 DA - 2015// TI - A molecular biomarker to diagnose community-acquired pneumonia on intensive care unit admission JO - Am J Respir Crit Care Med VL - 192 UR - https://doi.org/10.1164/rccm.201502-0355OC DO - 10.1164/rccm.201502-0355OC ID - Scicluna2015 ER - TY - JOUR AU - Bernard, G. R. AU - Artigas, A. AU - Brigham, K. L. AU - Carlet, J. AU - Falke, K. AU - Hudson, L. PY - 1994 DA - 1994// TI - The American-European Consensus Conference on ARDS. Definitions, mechanisms, relevant outcomes, and clinical trial coordination JO - Am J Respir Crit Care Med VL - 149 UR - https://doi.org/10.1164/ajrccm.149.3.7509706 DO - 10.1164/ajrccm.149.3.7509706 ID - Bernard1994 ER - TY - JOUR AU - Ranieri, V. M. AU - Rubenfeld, G. D. AU - Thompson, B. T. AU - Ferguson, N. D. AU - Caldwell, E. AU - Fan, E. PY - 2012 DA - 2012// TI - Acute respiratory distress syndrome: the Berlin Definition JO - JAMA VL - 307 ID - Ranieri2012 ER - TY - JOUR PY - 2015 DA - 2015// TI - Pediatric acute respiratory distress syndrome: consensus recommendations from the Pediatric Acute Lung Injury Consensus Conference JO - Pediatr Crit Care Med VL - 16 UR - https://doi.org/10.1097/PCC.0000000000000350 DO - 10.1097/PCC.0000000000000350 ID - ref11 ER - TY - JOUR AU - Luca, D. AU - Kaam, A. H. AU - Tingay, D. G. AU - Courtney, S. E. AU - Danhaive, O. AU - Carnielli, V. P. PY - 2017 DA - 2017// TI - The Montreux definition of neonatal ARDS: biological and clinical background behind the description of a new entity JO - Lancet Respir Med VL - 5 UR - https://doi.org/10.1016/S2213-2600(17)30214-X DO - 10.1016/S2213-2600(17)30214-X ID - Luca2017 ER - TY - JOUR AU - Ito, Y. AU - Betsuyaku, T. AU - Nagai, K. AU - Nasuhara, Y. AU - Nishimura, M. PY - 2005 DA - 2005// TI - Expression of pulmonary VEGF family declines with age and is further down-regulated in lipopolysaccharide (LPS)-induced lung injury JO - Exp Gerontol VL - 40 UR - https://doi.org/10.1016/j.exger.2005.01.009 DO - 10.1016/j.exger.2005.01.009 ID - Ito2005 ER - TY - JOUR AU - Ito, Y. AU - Betsuyaku, T. AU - Nasuhara, Y. AU - Nishimura, M. PY - 2007 DA - 2007// TI - Lipopolysaccharide-induced neutrophilic inflammation in the lungs differs with age JO - Exp Lung Res VL - 33 UR - https://doi.org/10.1080/01902140701634843 DO - 10.1080/01902140701634843 ID - Ito2007 ER - TY - JOUR AU - Smith, L. S. AU - Gharib, S. A. AU - Frevert, C. W. AU - Martin, T. R. PY - 2010 DA - 2010// TI - Effects of age on the synergistic interactions between lipopolysaccharide and mechanical ventilation in mice JO - Am J Respir Cell Mol Biol VL - 43 UR - https://doi.org/10.1165/rcmb.2009-0039OC DO - 10.1165/rcmb.2009-0039OC ID - Smith2010 ER - TY - JOUR AU - Yerkovich, S. T. AU - Chang, A. B. AU - Carroll, M. L. AU - Petsky, H. L. AU - Scrivener, G. AU - Upham, J. W. PY - 2012 DA - 2012// TI - Soluble receptor for advanced glycation end products (sRAGE) is present at high concentrations in the lungs of children and varies with age and the pattern of lung inflammation JO - Respirology VL - 17 UR - https://doi.org/10.1111/j.1440-1843.2012.02174.x DO - 10.1111/j.1440-1843.2012.02174.x ID - Yerkovich2012 ER - TY - JOUR AU - Zou, Y. AU - Yoon, S. AU - Jung, K. J. AU - Kim, C. H. AU - Son, T. G. AU - Kim, M. S. PY - 2006 DA - 2006// TI - Upregulation of aortic adhesion molecules during aging JO - J Gerontol A Biol Sci Med Sci VL - 61 UR - https://doi.org/10.1093/gerona/61.3.232 DO - 10.1093/gerona/61.3.232 ID - Zou2006 ER - TY - JOUR AU - Nomellini, V. AU - Brubaker, A. L. AU - Mahbub, S. AU - Palmer, J. L. AU - Gomez, C. R. AU - Kovacs, E. J. PY - 2012 DA - 2012// TI - Dysregulation of neutrophil CXCR18 and pulmonary endothelial icam-1 promotes age-related pulmonary inflammation JO - Aging Dis VL - 3 ID - Nomellini2012 ER - TY - JOUR AU - Richardson, D. K. AU - Corcoran, J. D. AU - Escobar, G. J. AU - Lee, S. K. PY - 2001 DA - 2001// TI - SNAP-II and SNAPPE-II: simplified newborn illness severity and mortality risk scores JO - J Pediatr VL - 138 UR - https://doi.org/10.1067/mpd.2001.109608 DO - 10.1067/mpd.2001.109608 ID - Richardson2001 ER - TY - JOUR AU - Slater, A. AU - Shann, F. AU - Pearson, G. PY - 2003 DA - 2003// TI - PIM2: a revised version of the Paediatric Index of Mortality JO - Intensive Care Med VL - 29 UR - https://doi.org/10.1007/s00134-002-1601-2 DO - 10.1007/s00134-002-1601-2 ID - Slater2003 ER - TY - JOUR AU - Zimmerman, J. E. AU - Kramer, A. A. AU - McNair, D. S. AU - Malila, F. M. AU - Shaffer, V. L. PY - 2006 DA - 2006// TI - Acute Physiology and Chronic Health Evaluation (APACHE) IV: hospital mortality assessment for today’s critically ill patients JO - Crit Care Med VL - 34 UR - https://doi.org/10.1097/01.CCM.0000215112.84523.F0 DO - 10.1097/01.CCM.0000215112.84523.F0 ID - Zimmerman2006 ER - TY - JOUR AU - Blic, J. AU - Midulla, F. AU - Barbato, A. AU - Clement, A. AU - Dab, I. AU - Eber, E. PY - 2000 DA - 2000// TI - Bronchoalveolar lavage in children. ERS Task Force on bronchoalveolar lavage in children JO - Eur Respir J VL - 15 UR - https://doi.org/10.1183/09031936.00.15121700 DO - 10.1183/09031936.00.15121700 ID - Blic2000 ER - TY - JOUR AU - Haslam, P. L. AU - Baughman, R. P. PY - 1999 DA - 1999// TI - Report of the European Respiratory Society Task force: guidelines for measurement of acellular components and recommendation for standardization of BAL JO - Eur Respir J VL - 14 UR - https://doi.org/10.1034/j.1399-3003.1999.14b01.x DO - 10.1034/j.1399-3003.1999.14b01.x ID - Haslam1999 ER - TY - JOUR AU - Matthay, M. A. AU - Ware, L. B. AU - Zimmerman, G. A. PY - 2012 DA - 2012// TI - The acute respiratory distress syndrome JO - J Clin Invest VL - 122 UR - https://doi.org/10.1172/JCI60331 DO - 10.1172/JCI60331 ID - Matthay2012 ER - TY - JOUR AU - Martin, T. R. AU - Ruzinski, J. T. AU - Wilson, C. B. AU - Skerrett, S. J. PY - 1995 DA - 1995// TI - Effects of endotoxin in the lungs of neonatal rats: age-dependent impairment of the inflammatory response JO - J Infect Dis VL - 171 UR - https://doi.org/10.1093/infdis/171.1.134 DO - 10.1093/infdis/171.1.134 ID - Martin1995 ER - TY - JOUR AU - Sordelli, D. O. AU - Djafari, M. AU - García, V. E. AU - Fontán, P. A. AU - Döring, G. PY - 1992 DA - 1992// TI - Age-dependent pulmonary clearance of Pseudomonas aeruginosa in a mouse model: diminished migration of polymorphonuclear leukocytes to N-formyl-methionyl-leucyl-phenylalanine JO - Infect Immun VL - 60 ID - Sordelli1992 ER - TY - JOUR AU - Kling, K. M. AU - Lopez-Rodriguez, E. AU - Pfarrer, C. AU - Mühlfeld, C. AU - Brandenberger, C. PY - 2017 DA - 2017// TI - Aging exacerbates acute lung injury-induced changes of the air-blood barrier, lung function, and inflammation in the mouse JO - Am J Physiol Lung Cell Mol Physiol VL - 312 UR - https://doi.org/10.1152/ajplung.00347.2016 DO - 10.1152/ajplung.00347.2016 ID - Kling2017 ER - TY - JOUR AU - Lawrence, S. M. AU - Corriden, R. AU - Nizet, V. PY - 2017 DA - 2017// TI - Age-appropriate functions and dysfunctions of the neonatal neutrophil JO - Front Pediatr VL - 5 ID - Lawrence2017 ER - TY - JOUR AU - Zonneveld, R. AU - Martinelli, R. AU - Shapiro, N. AU - Kuijpers, T. W. AU - Plötz, F. B. AU - Carman, C. V. PY - 2014 DA - 2014// TI - Soluble adhesion molecules as markers for sepsis and the potential pathophysiological discrepancy in neonates, children and adults JO - Crit Care VL - 18 UR - https://doi.org/10.1186/cc13733 DO - 10.1186/cc13733 ID - Zonneveld2014 ER - TY - JOUR AU - Bonnema, D. D. AU - Webb, C. S. AU - Pennington, W. R. AU - Stroud, R. E. AU - Leonardi, A. E. AU - Clark, L. L. PY - 2007 DA - 2007// TI - Effects of age on plasma matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinases (TIMPs) JO - J Card Fail VL - 13 UR - https://doi.org/10.1016/j.cardfail.2007.04.010 DO - 10.1016/j.cardfail.2007.04.010 ID - Bonnema2007 ER - TY - JOUR AU - Tayebjee, M. H. AU - Lip, G. Y. H. AU - Blann, A. D. AU - Macfadyen, R. J. PY - 2005 DA - 2005// TI - Effects of age, gender, ethnicity, diurnal variation and exercise on circulating levels of matrix metalloproteinases (MMP)-2 and -9, and their inhibitors, tissue inhibitors of matrix metalloproteinases (TIMP)-1 and -2 JO - Thromb Res VL - 115 UR - https://doi.org/10.1016/j.thromres.2004.08.023 DO - 10.1016/j.thromres.2004.08.023 ID - Tayebjee2005 ER - TY - JOUR AU - Winning, S. AU - Splettstoesser, F. AU - Fandrey, J. AU - Frede, S. PY - 2010 DA - 2010// TI - Acute hypoxia induces HIF-independent monocyte adhesion to endothelial cells through increased intercellular adhesion molecule-1 expression: the role of hypoxic inhibition of prolyl hydroxylase activity for the induction of NF-kappa B JO - J Immunol VL - 185 UR - https://doi.org/10.4049/jimmunol.0903244 DO - 10.4049/jimmunol.0903244 ID - Winning2010 ER - TY - JOUR AU - Khan, A. AU - Benthin, C. AU - Zeno, B. AU - Albertson, T. E. AU - Boyd, J. AU - Christie, J. D. PY - 2017 DA - 2017// TI - A pilot clinical trial of recombinant human angiotensin-converting enzyme 2 in acute respiratory distress syndrome JO - Crit Care VL - 21 UR - https://doi.org/10.1186/s13054-017-1823-x DO - 10.1186/s13054-017-1823-x ID - Khan2017 ER - TY - JOUR AU - Prescott, H. C. AU - Calfee, C. S. AU - Thompson, B. T. AU - Angus, D. C. AU - Liu, V. X. PY - 2016 DA - 2016// TI - Toward smarter lumping and smarter splitting: rethinking strategies for sepsis and acute respiratory distress syndrome clinical trial design JO - Am J Respir Crit Care Med VL - 194 UR - https://doi.org/10.1164/rccm.201512-2544CP DO - 10.1164/rccm.201512-2544CP ID - Prescott2016 ER - TY - JOUR AU - Supé, S. AU - Kohse, F. AU - Gembardt, F. AU - Kuebler, W. M. AU - Walther, T. PY - 2016 DA - 2016// TI - Therapeutic time window for angiotensin-(1-7) in acute lung injury JO - Br J Pharmacol VL - 173 UR - https://doi.org/10.1111/bph.13462 DO - 10.1111/bph.13462 ID - Supé2016 ER - TY - JOUR AU - Bos, L. D. AU - Martin-Loeches, I. AU - Schultz, M. J. PY - 2018 DA - 2018// TI - ARDS: challenges in patient care and frontiers in research JO - Eur Respir Rev VL - 27 UR - https://doi.org/10.1183/16000617.0107-2017 DO - 10.1183/16000617.0107-2017 ID - Bos2018 ER - TY - JOUR AU - Seok, J. AU - Warren, H. S. AU - Cuenca, A. G. AU - Mindrinos, M. N. AU - Baker, H. V. AU - Xu, W. PY - 2013 DA - 2013// TI - Genomic responses in mouse models poorly mimic human inflammatory diseases JO - Proc Natl Acad Sci USA VL - 110 UR - https://doi.org/10.1073/pnas.1222878110 DO - 10.1073/pnas.1222878110 ID - Seok2013 ER - TY - JOUR AU - Osuchowski, M. F. AU - Remick, D. G. AU - Lederer, J. A. AU - Lang, C. H. AU - Aasen, A. O. AU - Aibiki, M. PY - 2014 DA - 2014// TI - Abandon the mouse research ship? Not just yet! JO - Shock VL - 41 UR - https://doi.org/10.1097/SHK.0000000000000153 DO - 10.1097/SHK.0000000000000153 ID - Osuchowski2014 ER -