Skip to main content
Annals of Intensive Care

Table 2 Change from screening to hour 48 in total SOFA score and CV SOFA score

From: Sensitivity to angiotensin II dose in patients with vasodilatory shock: a prespecified analysis of the ATHOS-3 trial

 

Angiotensin II > 5 ng kg−1 min−1 (n = 84)

Angiotensin II ≤ 5 ng kg−1 min−1 (n = 79)

P value

Total SOFA score

 Mean (SD)

2.6 (5.5)

− 0.6 (5.0)

0.002a

 Median (range)

1.0 (− 6 to 15)

− 2.0 (− 10 to 15)

 

CV SOFA scoreb

 Mean (SD)

− 1.33 (1.7)

− 2.2 (1.7)

0.004

 Median (range)

0.0 (− 4 to 0)

− 3.0 (–4 to 0)

 
  1. CV, cardiovascular; MAP, mean arterial pressure; SOFA, Sequential Organ Failure Assessment; SD, standard deviation
  2. avan Elteren Wilcoxon rank test of angiotensin II dose at 30 min stratified by randomization strata for MAP and APACHE II score
  3. bAll patients had a CV SOFA score of 4 (highest risk) at screening based on inclusion/exclusion criteria. For patients missing a 48-hour assessment, the last observation was carried forward. In the event of death prior to the 48-hour assessment, the patient was assigned a CV SOFA score of 4. The van Elteren Wilcoxon rank test compared angiotensin II with placebo adjusting for randomization strata for MAP and APACHE II score
Back to article page