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Table 1 Recommendations according to the GRADE methodology

From: Formal guidelines: management of acute respiratory distress syndrome

  Recommendations according to the GRADE methodology
High level of proof Strong recommendation
 “…should be done…”
Grade 1 +
Moderate level of proof Optional recommendation
 “… should probably be done…”
Grade 2 +
Insufficient level of proof Recommendation in the form of an expert opinion
 “The experts suggest…”
Expert opinion
Moderate level of proof Optional recommendation
 “… should probably not be done…”
Grade 2 −
High level of proof Strong recommendation
 “…should not be done…”
Grade 1 −
Insufficient level of proof   No recommendation