Skip to main content

Table 1 Baseline characteristics of the study cohort

From: Inflammatory anemia-associated parameters are related to 28-day mortality in patients with sepsis admitted to the ICU: a preliminary observational study

  Control (n = 20) Survivor (n = 110) Non-survivor (n = 88) P valuea
Age (years) 65.6 (27–88) 69.9 (28–91) 68.7 (18–91) 0.732
Male [n (%)] 12 (60.0%) 74 (67.3%) 52 (59.1%) 0.234
Length of ICU stay (days) 15.5 (3.3–76.5) 13.8 (3.5–27.5) 0.535
Sources of sepsis [n (%)]     
 Lung 72 (65.5%) 52 (59.1%) 0.358
 Abdomen 9 (8.2%) 11 (12.5%) 0.316
 Bile 22 (20.0%) 16 (18.2%) 0.747
 Kidney 4 (3.6%) 5 (5.7%) 0.492
 Skin/soft tissue 3 (2.7%) 4 (4.5%) 0.491
Comorbidities [n (%)]     
 Hypertension 16 (14.5%) 15 (17.0%) 0.630
 Diabetes mellitus 27 (24.5%) 25 (28.4%) 0.539
 Stroke 14 (12.7%) 13 (14.8%) 0.677
 Acute myocardial infarction 2 (1.8%) 1 (1.1%) 0.697
 Deep venous thrombosis 3 (2.7%) 2 (2.3%) 0.839
Current smoker [n (%)] 2 (16.6%) 19 (17.3%) 17 (19.3%) 0.711
Postoperative patients [n (%)] 12 (10.9%) 10 (11.4%) 0.919
Patients using vasopressors on admission [n (%)] 6 (5.5%) 4 (4.5%) 0.322
Mechanical ventilation [n (%)] 41(37.3%) 79 (89.8%) < 0.01
Ventilation time (hours) 151.5 (0–672) 243.2 (0–660) < 0.01
PaO2/FiO2 406 (342–463) 244 (121–340) 183 (96–240) < 0.01
Procalcitonin (ng/mL) 0.02 (0.01–0.04) 3.16 (0.38–56.8) 6.56 (0.87–97.5) < 0.01
Lactate (mmol/L) 1.0 (0.5–1.7) 2.4 (1.3–3.5) 3.9 (1.8–6.2) < 0.01
Creatinine (µmol/L) 75 (41–100) 119 (56–188) 138 (65–198) < 0.01
Hemoglobin (g/L) 135 (130–144) 125 (103–163) 123 (100–161) 0.105
Reticulocytes (×109/L) 87 (76–107) 63 (38–92) 45 (27–68) < 0.01
Mean corpuscular volume (fL) 90 (85–98) 84 (76–94) 79 (69–89) < 0.01
Mean corpuscular hemoglobin (pg) 30 (28–33) 29 (24–34) 27 (22–31) < 0.01
MCHC (g/L) 335 (319–349) 329 (302–352) 306 (290–320) < 0.01
SOFA score 7 (4–13) 10 (6–15) < 0.01
  1. Values are the median (range)
  2. ICU intensive care unit; NS not significant; SOFA Sequential Organ Failure Assessment; MCHC mean corpuscular hemoglobin concentration
  3. aIndicates the P values for the comparison of survivor and non-survivor groups