| Control (n = 20) | Survivor (n = 110) | Non-survivor (n = 88) | P valuea |
---|---|---|---|---|
Age (years) | 65.6 (27–88) | 69.9 (28–91) | 68.7 (18–91) | 0.732 |
Male [n (%)] | 12 (60.0%) | 74 (67.3%) | 52 (59.1%) | 0.234 |
Length of ICU stay (days) | – | 15.5 (3.3–76.5) | 13.8 (3.5–27.5) | 0.535 |
Sources of sepsis [n (%)] | Â | Â | Â | Â |
 Lung | – | 72 (65.5%) | 52 (59.1%) | 0.358 |
 Abdomen | – | 9 (8.2%) | 11 (12.5%) | 0.316 |
 Bile | – | 22 (20.0%) | 16 (18.2%) | 0.747 |
 Kidney | – | 4 (3.6%) | 5 (5.7%) | 0.492 |
 Skin/soft tissue | – | 3 (2.7%) | 4 (4.5%) | 0.491 |
Comorbidities [n (%)] | Â | Â | Â | Â |
 Hypertension | – | 16 (14.5%) | 15 (17.0%) | 0.630 |
 Diabetes mellitus | – | 27 (24.5%) | 25 (28.4%) | 0.539 |
 Stroke | — | 14 (12.7%) | 13 (14.8%) | 0.677 |
 Acute myocardial infarction | — | 2 (1.8%) | 1 (1.1%) | 0.697 |
 Deep venous thrombosis | — | 3 (2.7%) | 2 (2.3%) | 0.839 |
Current smoker [n (%)] | 2 (16.6%) | 19 (17.3%) | 17 (19.3%) | 0.711 |
Postoperative patients [n (%)] | – | 12 (10.9%) | 10 (11.4%) | 0.919 |
Patients using vasopressors on admission [n (%)] | – | 6 (5.5%) | 4 (4.5%) | 0.322 |
Mechanical ventilation [n (%)] | – | 41(37.3%) | 79 (89.8%) | < 0.01 |
Ventilation time (hours) | – | 151.5 (0–672) | 243.2 (0–660) | < 0.01 |
PaO2/FiO2 | 406 (342–463) | 244 (121–340) | 183 (96–240) | < 0.01 |
Procalcitonin (ng/mL) | 0.02 (0.01–0.04) | 3.16 (0.38–56.8) | 6.56 (0.87–97.5) | < 0.01 |
Lactate (mmol/L) | 1.0 (0.5–1.7) | 2.4 (1.3–3.5) | 3.9 (1.8–6.2) | < 0.01 |
Creatinine (µmol/L) | 75 (41–100) | 119 (56–188) | 138 (65–198) | < 0.01 |
Hemoglobin (g/L) | 135 (130–144) | 125 (103–163) | 123 (100–161) | 0.105 |
Reticulocytes (×109/L) | 87 (76–107) | 63 (38–92) | 45 (27–68) | < 0.01 |
Mean corpuscular volume (fL) | 90 (85–98) | 84 (76–94) | 79 (69–89) | < 0.01 |
Mean corpuscular hemoglobin (pg) | 30 (28–33) | 29 (24–34) | 27 (22–31) | < 0.01 |
MCHC (g/L) | 335 (319–349) | 329 (302–352) | 306 (290–320) | < 0.01 |
SOFA score | – | 7 (4–13) | 10 (6–15) | < 0.01 |