Skip to main content

Table 2 Changes in inflammatory anemia-associated parameters of patients with sepsis in the first week of ICU admission in sepsis and control groups

From: Inflammatory anemia-associated parameters are related to 28-day mortality in patients with sepsis admitted to the ICU: a preliminary observational study

 

Control (n = 20)

Sepsis patients after ICU admission

Day 1 (n = 198)

Day 3 (n = 198)

Day 7 (n = 185)

Hemoglobin (g/L)

135 (130–144)

124 (100–163)a

103 (78–180)ab

95 (81–161)ab

RDW (%)

13.1 (12.5–13.5)

13.5 (11.5–19.9)

14.6 (11.9–20.1)a

14.5 (11.9–20.4)a

EPO (IU/L)

11.2 (9.9–12.6)

73.2 (20.8–428.4)a

34.3 (12.1–278.7)ab

17.3 (8.1–130.5)ab

sTfR (nmol/L)

15.1 (14.0–15.9)

20.3 (13.4–27.9)a

20.4 (13.5–28.1)a

21.5 (13.4–27.9)a

Hepcidin (ng/mL)

21.2 (20.0–22.8)

152.2 (60.2–231.5)a

80.6 (24.8–122.4)ab

51.1 (20.4–99.7)ab

Iron (µmol/L)

19.2 (14.5–20.4)

7.7 (5.3–10.8)a

6.7 (5.4–8.8)a

8.1 (5.4–11.4)a

Ferritin (ng/mL)

30.3 (29.5–31.4)

197.1 (85.2–302.8)a

565.6 (340.1–702.4)ab

306.4 (99.5–524.6)ab

IL-6 (pg/mL)

5.3 (3.0–7.7)

47.9 (15.7–171.9)a

33.7 (8.6–153.6)ab

33.0 (10.2–107.2)a

sTfR/log ferritin

10.2 (9.5–10.8)

8.9 (5.7–12.5)a

7.4 (4.8–10.4)a

8.8 (5.4–13.2)a

  1. Values are the mean ± standard deviation or median (range)
  2. EPO erythropoietin; ICU intensive care unit; IL-6 interleukin-6; RDW red blood cell distribution width; sTfR soluble transferrin receptor
  3. aP < 0.05 vs. control
  4. bP < 0.05 vs. day 1 of ICU admission