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Table 2 Changes in inflammatory anemia-associated parameters of patients with sepsis in the first week of ICU admission in sepsis and control groups

From: Inflammatory anemia-associated parameters are related to 28-day mortality in patients with sepsis admitted to the ICU: a preliminary observational study

  Control (n = 20) Sepsis patients after ICU admission
Day 1 (n = 198) Day 3 (n = 198) Day 7 (n = 185)
Hemoglobin (g/L) 135 (130–144) 124 (100–163)a 103 (78–180)ab 95 (81–161)ab
RDW (%) 13.1 (12.5–13.5) 13.5 (11.5–19.9) 14.6 (11.9–20.1)a 14.5 (11.9–20.4)a
EPO (IU/L) 11.2 (9.9–12.6) 73.2 (20.8–428.4)a 34.3 (12.1–278.7)ab 17.3 (8.1–130.5)ab
sTfR (nmol/L) 15.1 (14.0–15.9) 20.3 (13.4–27.9)a 20.4 (13.5–28.1)a 21.5 (13.4–27.9)a
Hepcidin (ng/mL) 21.2 (20.0–22.8) 152.2 (60.2–231.5)a 80.6 (24.8–122.4)ab 51.1 (20.4–99.7)ab
Iron (µmol/L) 19.2 (14.5–20.4) 7.7 (5.3–10.8)a 6.7 (5.4–8.8)a 8.1 (5.4–11.4)a
Ferritin (ng/mL) 30.3 (29.5–31.4) 197.1 (85.2–302.8)a 565.6 (340.1–702.4)ab 306.4 (99.5–524.6)ab
IL-6 (pg/mL) 5.3 (3.0–7.7) 47.9 (15.7–171.9)a 33.7 (8.6–153.6)ab 33.0 (10.2–107.2)a
sTfR/log ferritin 10.2 (9.5–10.8) 8.9 (5.7–12.5)a 7.4 (4.8–10.4)a 8.8 (5.4–13.2)a
  1. Values are the mean ± standard deviation or median (range)
  2. EPO erythropoietin; ICU intensive care unit; IL-6 interleukin-6; RDW red blood cell distribution width; sTfR soluble transferrin receptor
  3. aP < 0.05 vs. control
  4. bP < 0.05 vs. day 1 of ICU admission