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Table 3 Comparison of inflammatory anemia-associated parameters and creatinine levels of patients with sepsis in survivor and non-survivor groups

From: Inflammatory anemia-associated parameters are related to 28-day mortality in patients with sepsis admitted to the ICU: a preliminary observational study

 

After ICU admission

Day 1

Day 3

Day 7

Hemoglobin (g/L)

   

 Survivor

125 (103–163)

106 (90–180)

95 (81–160)

 Non-survivor

123 (100–161)

99 (78–155)

95 (80–112)

RDW (%)

   

 Survivor

13.3 (11.5–19.0)

14.0 (11.9–19.8)

13.9 (11.9–18.7)

 Non-survivor

14.2 (11.8–19.9)

15.4 (12.2–20.1)a

15.3 (12.5–20.4)a

EPO (IU/L)

   

Survivor

93.8 (49.6–428.4)

44.7 (20.0–278.7)b

20.7 (10.9–130.5)b

Non-survivor

51.3 (20.8–126.2)a

23.1 (12.1–81.4)ab

11.1 (8.1–29.4)ab

sTfR (nmol/L)

   

 Survivor

20.2 (13.5–27.9)

20.4 (13.5–27.8)

21.7 (13.7–27.9)

 Non-survivor

20.7 (13.4–28.0)

20.5 (13.6–28.1)

19.6 (13.4–27.4)

Hepcidin (ng/mL)

   

 Survivor

133.9 (60.2–185.5)

66.3 (24.8–95.3)b

45.7 (20.4–69.3)b

 Non-survivor

172.2 (110.1–231.5)a

99.8 (45.9–122.4)ab

65.6 (35.2–99.7)ab

Iron (µmol/L)

   

 Survivor

8.1 (2.3–12.5)

8.6 (2.4–15.4)

10.6 (3.3–19.4)

 Non-survivor

7.6 (2.3–15.7)

6.3 (2.9–8.2)a

6.6 (3.0–11.4)a

Ferritin (ng/mL)

   

 Survivor

172.5 (85.2–237.1)

555.0 (340.1–615.8)b

276.7 (99.5–524.6)b

 Non-survivor

227.1 (110.7–302.8)a

581.9 (423.9–702.4)ab

322.5 (218.6–364.6)a

IL–6 (pg/mL)

   

 Survivor

34.2 (15.7–55.5)

23.3 (8.6–45.3)b

21.9 (11.7–89.0)b

 Non-survivor

124.3 (49.3–171.9)a

76.0 (29.0–153.6)ab

44.9 (10.2–107.2)ab

sTfR/log ferritin

   

 Survivor

9.0 (6.1–12.5)

7.5 (4.9–10.4)

9.3 (5.5–13.2)

 Non-survivor

8.8 (5.7–11.9)

6.3 (4.9–10.3)a

7.9 (5.4–11.0)a

Creatinine (µmol/L)

   

 Survivor

119 (56–188)

132 (114–201)

124 (67–196)

 Non-survivor

138 (65–198)a

176 (114–235)ab

217 (115–311)ab

  1. Values are the mean ± standard deviation or median (range)
  2. EPO erythropoietin; IL-6 interleukin-6; RDW red blood cell distribution width; sTfR soluble transferrin receptor
  3. aP < 0.05 vs. survivor
  4. bP < 0.05 vs. day 1 of ICU admission