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Table 3 Comparison of inflammatory anemia-associated parameters and creatinine levels of patients with sepsis in survivor and non-survivor groups

From: Inflammatory anemia-associated parameters are related to 28-day mortality in patients with sepsis admitted to the ICU: a preliminary observational study

  After ICU admission
Day 1 Day 3 Day 7
Hemoglobin (g/L)    
 Survivor 125 (103–163) 106 (90–180) 95 (81–160)
 Non-survivor 123 (100–161) 99 (78–155) 95 (80–112)
RDW (%)    
 Survivor 13.3 (11.5–19.0) 14.0 (11.9–19.8) 13.9 (11.9–18.7)
 Non-survivor 14.2 (11.8–19.9) 15.4 (12.2–20.1)a 15.3 (12.5–20.4)a
EPO (IU/L)    
Survivor 93.8 (49.6–428.4) 44.7 (20.0–278.7)b 20.7 (10.9–130.5)b
Non-survivor 51.3 (20.8–126.2)a 23.1 (12.1–81.4)ab 11.1 (8.1–29.4)ab
sTfR (nmol/L)    
 Survivor 20.2 (13.5–27.9) 20.4 (13.5–27.8) 21.7 (13.7–27.9)
 Non-survivor 20.7 (13.4–28.0) 20.5 (13.6–28.1) 19.6 (13.4–27.4)
Hepcidin (ng/mL)    
 Survivor 133.9 (60.2–185.5) 66.3 (24.8–95.3)b 45.7 (20.4–69.3)b
 Non-survivor 172.2 (110.1–231.5)a 99.8 (45.9–122.4)ab 65.6 (35.2–99.7)ab
Iron (µmol/L)    
 Survivor 8.1 (2.3–12.5) 8.6 (2.4–15.4) 10.6 (3.3–19.4)
 Non-survivor 7.6 (2.3–15.7) 6.3 (2.9–8.2)a 6.6 (3.0–11.4)a
Ferritin (ng/mL)    
 Survivor 172.5 (85.2–237.1) 555.0 (340.1–615.8)b 276.7 (99.5–524.6)b
 Non-survivor 227.1 (110.7–302.8)a 581.9 (423.9–702.4)ab 322.5 (218.6–364.6)a
IL–6 (pg/mL)    
 Survivor 34.2 (15.7–55.5) 23.3 (8.6–45.3)b 21.9 (11.7–89.0)b
 Non-survivor 124.3 (49.3–171.9)a 76.0 (29.0–153.6)ab 44.9 (10.2–107.2)ab
sTfR/log ferritin    
 Survivor 9.0 (6.1–12.5) 7.5 (4.9–10.4) 9.3 (5.5–13.2)
 Non-survivor 8.8 (5.7–11.9) 6.3 (4.9–10.3)a 7.9 (5.4–11.0)a
Creatinine (µmol/L)    
 Survivor 119 (56–188) 132 (114–201) 124 (67–196)
 Non-survivor 138 (65–198)a 176 (114–235)ab 217 (115–311)ab
  1. Values are the mean ± standard deviation or median (range)
  2. EPO erythropoietin; IL-6 interleukin-6; RDW red blood cell distribution width; sTfR soluble transferrin receptor
  3. aP < 0.05 vs. survivor
  4. bP < 0.05 vs. day 1 of ICU admission