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Table 5 Performance of inflammatory anemia-associated parameters and SOFA score on day 1 of ICU admission for predicting 28-day mortality in patients with sepsis

From: Inflammatory anemia-associated parameters are related to 28-day mortality in patients with sepsis admitted to the ICU: a preliminary observational study

  Cutoff Sensitivity (%) Specificity (%) PPV (%) NPV (%) Youden (%) LR+ LR–
EPO 52.6 IU/L 83.0 68.2 67.6 83.3 51.1 2.61 0.25
Hepcidin 142.6 ng/mL 65.9 87.3 80.6 76.2 53.2 5.19 0.39
Ferritin 207.2 ng/mL 69.3 70.0 64.9 74.0 39.3 2.31 0.44
IL-6 89.1 pg/mL 73.9 66.4 63.7 76.0 40.2 2.20 0.39
RDW 13.7% 86.4 49.1 57.6 81.8 35.5 1.70 0.28
sTfR/log ferritin 8.4 nmol/L 58.0 81.8 71.8 70.9 39.8 3.19 0.51
SOFA score 8.5 78.4 80.0 75.8 82.2 58.4 3.92 0.27
  1. EPO erythropoietin; ICU intensive care unit; IL-6 interleukin-6; LR + positive likelihood ratio; LR– negative likelihood ratio; NPV negative predictive value; PPV positive predictive value; RDW red blood cell distribution width; SOFA Sequential Organ Failure Assessment; sTfR soluble transferrin receptor