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Table 1 Patient characteristics and outcomes according to separation attempt

From: Outcomes of mechanical ventilation according to WIND classification in pediatric patients

 

Total patients (n = 224)

SA group (n = 180)

No-SA group (n = 44)

p value

Baseline characteristics

Age in years

2.1 (0.5–6.6)

1.6 (0.4–5.5)

5.3 (1.2–13.0)

0.001

Male

122 (54.5)

102 (56.7)

20 (45.5)

0.121

PIM 3 (%), median (IQR)

4.6 (1.4–15.0)

3.0 (0.9–8.2)

22.3 (7.0–84.0)

<0.001

PIM 3 (%), mean (SD)

15.5 (26.0)

10.5 (20.0)

36.2 (36.0)

 

Admission type

    

 Postoperative admission

37 (16.5)

35 (19.4)

2 (4.5)

0.010

 Medical admission

187 (83.5)

145 (80.6)

42 (95.5)

0.009

  Respiratory

117 (52.2)

98 (67.6)

19 (45.2)

 

  Cardiovascular

33 (14.7)

21 (14.5)

12 (28.6)

 

  Neurologic

20 (8.9)

17 (11.7)

3 (7.1)

 

  Other

17 (7.7)

9 (6.2)

8 (19.1)

 

Underlying disease

   

0.001

 Neurologic

49 (21.9)

40 (22.2)

7 (15.9)

 

 Pulmonary

47 (21.0)

20 (11.1)

1 (2.3)

 

 Cardiologic

47 (21.0)

40 (22.2)

7 (15.9)

 

 Oncologic

21 (9.4)

27 (15.0)

22 (50.0)

 

 Infectious

19 (8.5)

16 (8.9)

3 (6.8)

 

 Other

41 (18.3)

37 (21.0)

4 (9.1)

 

Clinical outcomes

Total MV duration, days

7.0 (4–14)

7.0 (4–13)

12.5 (6.0–31.5)

< 0.001

Ventilator-free daysa

19 (0–24)

21 (15–24)

0

< 0.001

Length of ICU stay, days

12 (7–21.7)

12.0 (7–21)

13.0 (6.0–31.7)

0.448

ICU-free daysa

13 (0–20)

16 (7–21)

0 (0–0)

< 0.001

Length of hospital stay, days

26 (14–48)

24.0 (14–48)

33.5 (13.3–58.0)

0.753

Status at ICU discharge

    

 Dead

46 (20.5)

5 (2.8)

41 (93.2)

< 0.001

 Alive and weaned

    

  Spontaneous breathing

144 (64.3)

144 (80.0)

0

 

  Tracheostomy, no MV

22 (9.8)

22 (12.2)

0

 

 Alive and not weaned

    

  Tracheostomy with MV

12 (5.4)

9 (5.0)

3 (6.8)

 
  1. Data are presented as n (%) or median (interquartile range)
  2. SA separation attempt, IQR interquartile range, SD standard deviation, PIM 3 pediatric index of mortality 3, MV mechanical ventilation, ICU intensive care unit
  3. aVentilator-free days/ICU-free days were calculated as the number of days without mechanical ventilation/ICU admission to day 28. Non-survivors were calculated as a value of 0