Skip to main content

Table 1 Patient characteristics and outcomes according to separation attempt

From: Outcomes of mechanical ventilation according to WIND classification in pediatric patients

  Total patients (n = 224) SA group (n = 180) No-SA group (n = 44) p value
Baseline characteristics
Age in years 2.1 (0.5–6.6) 1.6 (0.4–5.5) 5.3 (1.2–13.0) 0.001
Male 122 (54.5) 102 (56.7) 20 (45.5) 0.121
PIM 3 (%), median (IQR) 4.6 (1.4–15.0) 3.0 (0.9–8.2) 22.3 (7.0–84.0) <0.001
PIM 3 (%), mean (SD) 15.5 (26.0) 10.5 (20.0) 36.2 (36.0)  
Admission type     
 Postoperative admission 37 (16.5) 35 (19.4) 2 (4.5) 0.010
 Medical admission 187 (83.5) 145 (80.6) 42 (95.5) 0.009
  Respiratory 117 (52.2) 98 (67.6) 19 (45.2)  
  Cardiovascular 33 (14.7) 21 (14.5) 12 (28.6)  
  Neurologic 20 (8.9) 17 (11.7) 3 (7.1)  
  Other 17 (7.7) 9 (6.2) 8 (19.1)  
Underlying disease     0.001
 Neurologic 49 (21.9) 40 (22.2) 7 (15.9)  
 Pulmonary 47 (21.0) 20 (11.1) 1 (2.3)  
 Cardiologic 47 (21.0) 40 (22.2) 7 (15.9)  
 Oncologic 21 (9.4) 27 (15.0) 22 (50.0)  
 Infectious 19 (8.5) 16 (8.9) 3 (6.8)  
 Other 41 (18.3) 37 (21.0) 4 (9.1)  
Clinical outcomes
Total MV duration, days 7.0 (4–14) 7.0 (4–13) 12.5 (6.0–31.5) < 0.001
Ventilator-free daysa 19 (0–24) 21 (15–24) 0 < 0.001
Length of ICU stay, days 12 (7–21.7) 12.0 (7–21) 13.0 (6.0–31.7) 0.448
ICU-free daysa 13 (0–20) 16 (7–21) 0 (0–0) < 0.001
Length of hospital stay, days 26 (14–48) 24.0 (14–48) 33.5 (13.3–58.0) 0.753
Status at ICU discharge     
 Dead 46 (20.5) 5 (2.8) 41 (93.2) < 0.001
 Alive and weaned     
  Spontaneous breathing 144 (64.3) 144 (80.0) 0  
  Tracheostomy, no MV 22 (9.8) 22 (12.2) 0  
 Alive and not weaned     
  Tracheostomy with MV 12 (5.4) 9 (5.0) 3 (6.8)  
  1. Data are presented as n (%) or median (interquartile range)
  2. SA separation attempt, IQR interquartile range, SD standard deviation, PIM 3 pediatric index of mortality 3, MV mechanical ventilation, ICU intensive care unit
  3. aVentilator-free days/ICU-free days were calculated as the number of days without mechanical ventilation/ICU admission to day 28. Non-survivors were calculated as a value of 0