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Table 1 Baseline characteristics of the patients (n = 19)

From: PEEP titration in moderate to severe ARDS: plateau versus transpulmonary pressure

Characteristic  
Male, n (%) 13 (68.4)
Age (years) 72 ± 10
Body mass index (kg/m2) 28 ± 6
SAPS II score 65 ± 15
Etiology of ARDS, n (%)
 Pneumonia/aspiration 16 (84.2)
 Sepsis 2 (10.5)
 Pancreatitis 1 (5.3)
Organ failure at baseline (SOFA), n (%)
 Hemodynamic 18 (94.7)
 Renal 9 (47.4)
 Hepatic 0 (0)
 Hematological 2 (10.5)
Arterial blood gas
 PaO2/FiO2 ratio 92 ± 31
 FiO2 (%) 80 ± 21
 pH 7.31 ± 0.11
 PaCO2 (mmHg) 45 ± 10
 HCO3- (mmol/l) 22.4 ± 4.0
 Base excess − 3.4 ± 5.1
 Lactates (mmol/l) 1.6 ± 1.0
Hemodynamic variables
 Heart rate (beats/min) 99 ± 27
 Systolic arterial pressure (mmHg) 127 ± 23
 Diastolic arterial pressure (mmHg) 59 ± 12
 Mean arterial pressure (mmHg) 82 ± 13
Respiratory mechanics
 Minute ventilation (L/min) 9.6 ± 1.6
 Tidal volume (ml/kg PBW) 6.1 ± 0.4
 EELV (ml) 1319 ± 626
Aspect of ARDS, n (%)
 Patchy 6 (31.6)
 Diffuse 10 (52.6)
 Focal 3 (15.8)
 Mortality at Hospital discharge 10/19 (53%)
  1. Results are expressed as number (%), or mean ± standard deviation
  2. SAPS 2: Simplified Acute Physiology Score 2; ARDS: acute respiratory distress syndrome; PBW: predicted body weight. SOFA: sepsis-related organ failure assessment; EELV: end-expiratory lung volume (ml)