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Table 1 Recommendations according to the GRADE methodology

From: Diagnosis and management of metabolic acidosis: guidelines from a French expert panel

  Recommendation according to the GRADE methodology  
High level of evidence Strong recommendation
“… should be done…”
Grade 1+
Moderate level of evidence Optional recommendation
“… should probably be done…”
Grade 2+
Insufficient level of evidence Recommendation in the form of an expert opinion
“The experts suggest…”
Expert opinion
Moderate level of evidence Optional recommendation
“… should probably not be done…”
Grade 2−
High level of evidence Strong recommendation
“… should not be done…”
Grade 1−