Overall | SBT success (n = 61) | SBT failure (n = 17) | p value | Extubation success (n = 39) | Extubation failure (n = 22) | p value | |
---|---|---|---|---|---|---|---|
Characteristics at ICU admission | |||||||
Weight (kg) | 75 [65; 83] | 75 [65; 81] | 75 [68; 95] | 0.458 | 70 [62; 80] | 80 [70; 86] | 0.128 |
Height (cm) | 170 [165; 173] | 170 [165; 175] | 170 [163; 170] | 0.286 | 170 [165; 175] | 170 [160; 172] | 0.203 |
SAPS-II | 52 [37; 67] | 50 [34; 66] | 59 [41; 68] | 0.188 | 44 [31; 55] | 63 [48; 83] | < 0.001 |
SOFA | 6 [4; 9] | 6 [4; 9] | 4 [3; 7] | 0.049 | 6 [4; 9] | 7 [4; 10] | 0.790 |
Risk factors for post-extubation respiratory failure | |||||||
PaCO2 > 45 mmHg at SBT n (%) | 30 (38) | 22 (36) | 8 (47) | 0.416 | 12 (31) | 10 (45) | 0.279 |
Chronic respiratory disease n (%) | 17 (22) | 12 (20) | 5 (29) | 0.510 | 7 (18) | 5 (23) | 0.741 |
Chronic heart failure n (%) | 17 (22) | 12 (20) | 5 (29) | 0.510 | 9 (23) | 3 (14) | 0.510 |
Upper airway stridor n (%) | 2 (3) | 2 (3) | 0 (0) | > 0.999 | 2 (5) | 0 (0) | 0.531 |
Age ≥ 65 years n (%) | 48 (62) | 38 (62) | 10 (59) | 0.786 | 24 (62) | 14 (64) | > 0.999 |
Cardiac failure as reason of iMV n (%) | 10 (13) | 8 (13) | 2 (12) | > 0.999 | 6 (15) | 2 (9) | 0.699 |
APACHE-II score > 12 at extubation n (%) | 29 (37) | 24 (39) | 5 (29) | 0.575 | 14 (36) | 10 (45) | 0.587 |
ARF requiring > 72 h of iMV n (%) | 44 (56) | 30 (49) | 14 (82) | 0.025 | 19 (49) | 11 (48) | > 0.999 |
BMI > 35 kg/m2 n (%) | 11 (14) | 5 (8) | 6 (35) | 0.011 | 3 (8) | 2 (9) | > 0.999 |
Neuromuscular disease n (%) | 9 (12) | 4 (7) | 5 (29) | 0.020 | 3 (8) | 1 (5) | > 0.999 |
Reason for ICU admission | |||||||
Acute heart failure n (%) | 10 (13) | 6 (10) | 4 (23) | 0.212 | 0 (0) | 6 (27) | 0.013 |
Acute on Chronic respiratory failure n (%) | 17 (22) | 12 (20) | 5 (29) | 0.507 | 7 (18) | 5 (23) | 0.742 |
Sepsis/septic shock n (%) | 21 (27) | 20 (33) | 1 (6) | 0.031 | 14 (36) | 6 (27) | 0.577 |
Trauma n (%) | 10 (13) | 7 (11) | 3 (18) | 0.682 | 7 (18) | 0 (0) | 0.042 |
Pneumonia n (%) | 20 | 16 (26) | 4 (24) | > 0.999 | 11 (28) | 5 (23) | 0.766 |
Characteristics before the SBT | |||||||
PEEP (cmH2O) | 5.0 [5.0; 5.1] | 5.0 [5.0; 5.1] | 5.0 [5.0; 5.0] | 0.168 | 5.0 [5.0; 5.1] | 5.0 [5.0; 5.1] | 0.953 |
Inspiratory support (cmH2O) | 10 [8; 11] | 10 [8; 10] | 10 [9; 11] | 0.531 | 9 [8; 11] | 10 [10; 10] | 0.118 |
pH | 7.44 [7.41; 7.47] | 7.44 [7.40; 7.48] | 7.46 [7.42; 7.48] | 0.546 | 7.45 [7.41; 7.48] | 7.42 [7.40; 7.45] | 0.397 |
PaCO2 (mmHg) | 39.3 [36.3; 45.0] | 39.3 [36.0; 45.0] | 39.5 [38.2; 44.4] | 0.392 | 38.5 [34.0; 44.3] | 39.3 [38.0; 47.3] | 0.176 |
PaO2/FiO2 (mmHg) | 268 [230; 310] | 274 [241; 306] | 248 [205; 324] | 0.347 | 274 [243; 303] | 270 [226; 313] | 0.932 |