Table 2 Biomarker levels and fluid administration
Biomarker level (ng/mL) at 0 h (median [IQR]) | Fluid administration | |||
|---|---|---|---|---|
1st tertile, n = 205 (4–201 mL/h) | 2nd tertile, n = 206 (202–314 mL/h) | 3rd tertile, n = 208 (315–2824 mL/h) | p value | |
Syndecan-1 | 105.70 [56.65–205.20] | 109.05 [64.93–194.25] | 114.45 [64.08–231.85] | 0.276 |
Angiopoietin-2 | 6.10 [3.40–11.64] | 6.97 [3.63–11.98] | 5.92 [3.06–13.31] | 0.669 |
Soluble thrombomodulin | 5.03 [3.94–6.93] | 5.50 [4.18–7.07] | 5.53 [3.91–7.72] | 0.282 |
Vascular adhesion protein-1 | 279.00 [195.50–395.50] | 244.50 [170.75–355.25] | 214.50 [148.00–305.00] | < 0.001 |
Interleukin-6 | 0.22 [0.07–1.00] | 0.49 [0.16–0.36] | 3.17 [0.45–19.51] | < 0.001 |