Fig. 3
From: Nephrotoxic drug burden among 1001 critically ill patients: impact on acute kidney injury
Severity of disease sensitivity analysis. Squares represent mean values of the nephrotoxic burden prior to the index day with error bars indicating 95% confidence interval (IC95). Whereas nephrotoxic burden prior to the index day was higher among cases than controls in the overall population [bottom line: associated odds ratio (OR) 1.20, IC95 1.04–1.38] and among patients with a simplified acute physiology score 2 (SAPS2) below the median value of the population (SAPS2 = 48) indicating lower severity of disease (upper line, associated OR 1.26 IC95 1.03–1.56), no such association was observed among the most severe patients (SAPS2 > 48, middle line, associated OR 1.13 IC95 0.92–1.37)