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Table 1 Evidence grading and recommendations formulation

From: Management of severe asthma exacerbation: guidelines from the Société Française de Médecine d’Urgence, the Société de Réanimation de Langue Française and the French Group for Pediatric Intensive Care and Emergencies

  Recommendations formulation according to GRADE
High level of evidence Strong recommendation «should be…» Grade 1+
Intermediate to low level of evidence Optional recommendation «should probably…» Grade 2+
No or insufficient available data Expert opinion «the experts recommend…» Expert opinion
Intermediate to low level of evidence Optional recommendation «should probably not…» Grade 2−
High level of evidence Strong recommendation «should not be…» Grade 1−