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Table 2 Univariate and multivariate analyses for risk factors associated with NIV failure in the derivation cohort

From: Early prediction of noninvasive ventilation failure in COPD patients: derivation, internal validation, and external validation of a simple risk score

 Univariate analyses
OR (95% CI)
pMultivariate analyses
OR (95% CI)
p
Chronic kidney disease2.219 (1.147–4.292)0.02
APACHE II score1.208 (1.150–1.270)< 0.01
Data collected before NIV
 Heart rate, beats/min1.025 (1.014–1.037)< 0.01
 pH0.004 (0.000–0.084)< 0.01
 PaO2/FiO2, mmHg0.996 (0.993–0.999)0.01
 GCS0.651 (0.558–0.759)< 0.01
Data collected at 1–2 h of NIV
 Respiratory rate, breaths/min1.122 (1.076–1.170)< 0.011.064 (1.001–1.131)0.05
 Heart rate, beats/min1.035 (1.024–1.047)< 0.011.027 (1.011–1.043)< 0.01
 Systolic blood pressure, mmHg1.015 (1.005–1.024)< 0.01
 Diastolic blood pressure, mmHg1.027 (1.011–1.044)< 0.01
 pH0.000 (0.000–0.000)< 0.010.000 (0.000–0.000)< 0.01
 PaCO2, mmHg1.037 (1.024–1.051)< 0.01
 PaO2/FiO2, mmHg0.991 (0.987–0.994)< 0.010.995 (0.990–0.999)0.02
 GCS0.331 (0.245–0.447)< 0.010.371 (0.269–0.512)< 0.01
  1. NIV noninvasive ventilation, OR odds ratio, CI confidence interval, GCS Glasgow coma scale