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Table 2 Univariate and multivariate analyses for risk factors associated with NIV failure in the derivation cohort

From: Early prediction of noninvasive ventilation failure in COPD patients: derivation, internal validation, and external validation of a simple risk score

 

Univariate analyses

OR (95% CI)

p

Multivariate analyses

OR (95% CI)

p

Chronic kidney disease

2.219 (1.147–4.292)

0.02

APACHE II score

1.208 (1.150–1.270)

< 0.01

Data collected before NIV

 Heart rate, beats/min

1.025 (1.014–1.037)

< 0.01

 pH

0.004 (0.000–0.084)

< 0.01

 PaO2/FiO2, mmHg

0.996 (0.993–0.999)

0.01

 GCS

0.651 (0.558–0.759)

< 0.01

Data collected at 1–2 h of NIV

 Respiratory rate, breaths/min

1.122 (1.076–1.170)

< 0.01

1.064 (1.001–1.131)

0.05

 Heart rate, beats/min

1.035 (1.024–1.047)

< 0.01

1.027 (1.011–1.043)

< 0.01

 Systolic blood pressure, mmHg

1.015 (1.005–1.024)

< 0.01

 Diastolic blood pressure, mmHg

1.027 (1.011–1.044)

< 0.01

 pH

0.000 (0.000–0.000)

< 0.01

0.000 (0.000–0.000)

< 0.01

 PaCO2, mmHg

1.037 (1.024–1.051)

< 0.01

 PaO2/FiO2, mmHg

0.991 (0.987–0.994)

< 0.01

0.995 (0.990–0.999)

0.02

 GCS

0.331 (0.245–0.447)

< 0.01

0.371 (0.269–0.512)

< 0.01

  1. NIV noninvasive ventilation, OR odds ratio, CI confidence interval, GCS Glasgow coma scale