Cutoff point | AUC (95% CI) | SE (%) | SP (%) | PPV (%) | NPV (%) | LR+ | LR− | |
---|---|---|---|---|---|---|---|---|
Derivation cohort | ||||||||
Prediction of NIV failure | > 5 | 0.90 (0.87–0.92) | 70.2 | 92.6 | 68.8 | 93.1 | 9.50 | 0.32 |
Prediction of early NIV failure | > 5 | 0.91 (0.88–0.93) | 81.3 | 89.9 | 54.2 | 97.0 | 8.05 | 0.21 |
Internal-validation cohort | ||||||||
Prediction of NIV failure | > 5 | 0.89 (0.85–0.92) | 77.1 | 93.5 | 73.4 | 94.6 | 11.9 | 0.25 |
Prediction of early NIV failure | > 5 | 0.96 (0.94–0.98) | 93.9 | 88.6 | 48.4 | 99.2 | 8.26 | 0.07 |
External-validation cohort | ||||||||
Prediction of NIV failure | > 5 | 0.71 (0.67–0.76) | 62.9 | 75.8 | 20.2 | 95.5 | 2.60 | 0.49 |
Prediction of early NIV failure | > 5 | 0.83 (0.79–0.87) | 77.8 | 74.8 | 12.8 | 98.6 | 3.09 | 0.30 |