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Table 1 Patients’ characteristics at ICU admission

From: Direct admission to the intensive care unit from the emergency department and mortality in critically ill hematology patients

Characteristics Overall cohort (N = 1008) Status at hospital discharge Missing data
Alive (n = 613) Death (n = 395)
Age, median [IQR], years 60 [49–69] 59 [47–68] 62 [52–71] 0
Female gender, n (%) 396 (39.3) 252 (41.1) 144 (36.4) 0
Underlying malignancy, n (%) 0
 Non-Hodgkin’s lymphoma 319 (31.6) 190 (31.0) 129 (32.7)  
 Acute myeloid leukemia 274 (27.2) 162 (26.4) 112 (28.4)  
 Myeloma 126 (12.5) 86 (14.0) 40 (10.1)  
 Chronic lymphocytic leukemia 75 (7.4) 45 (7.3) 30 (7.6)  
 Acute lymphocytic leukemia 73 (7.2) 44 (7.2) 29 (7.3)  
 Myelodysplastic syndrome 46 (4.6) 26 (4.2) 20 (5.1)  
 Hodgkin’s disease 25 (2.5) 18 (2.9) 7 (1.8)  
 Chronic myeloid leukemia 19 (1.9) 14 (2.3) 5 (1.3)  
 Other 51 (5.1) 28 (4.5) 23 (5.8)  
Disease status, n (%) 54
 Complete or partial remission 232 (24.3) 154 (26.6) 78 (20.7)  
 Newly diagnosed 382 (40.0) 238 (41.2) 144 (38.2)  
 Other 340 (35.6) 185 (32.1) 155 (41.1)  
Days since diagnosis, median [IQR] 169 [7–965] 163 [7–1015] 174 [10–942] 97
Allogeneic BMT/HSCT recipient, n (%) 146 (14.5) 70 (11.4) 76 (19.3) 3
Long course corticosteroids, n (%) 381 (38) 218 (35.7) 163 (41.6) 5
Charlson comorbidity index, median [IQR] 4 [3–6] 4 [2–5] 4 [3–6] 1
Poor PS (> 2), n (%) 198 (19.8) 85 (13.9) 113 (28.8) 6
Reason for ICU admission, n (%) 55
 Acute respiratory failure 374 (39.2) 205 (35.6) 169 (44.8)  
 Sepsis or septic shock 255 (26.8) 166 (28.8) 89 (23.6)  
 Metabolic disorder or acute kidney injury 111 (11.6) 73 (12.7) 38 (10.1)  
 Coma 69 (7.2) 41 (7.1) 28 (7.4)  
 Other 144 (15.5) 91 (15.8) 53 (14.1)  
Organ failure, n (%) 2
 Respiratory 631 (62.7) 344 (56.1) 287 (73.0)  
 Hemodynamic 426 (42.3) 236 (38.5) 190 (48.3)  
 Renal 305 (30.3) 171 (27.9) 134 (34.0)  
 Neurological 226 (22.4) 114 (18.6) 112 (28.4)  
 Coagulation 194 (19.3) 99 (16.1) 95 (24.2)  
 Hepatic 83 (8.3) 39 (6.4) 44 (11.2)  
 Multi-organ 549 (54.5) 289 (47.1) 260 (66.0)  
SOFA score, median [IQR] 6 [3–9] 5 [3–7] 7 [5–11] 1
  1. BMT bone marrow transplantation, HSCT hematopoietic stem-cell transplantation, ICU intensive care unit, IQR interquartile range, PS performance status, SOFA Sequential Related Organ Failure Assessment